Acetaminophen-induced toxic epidermal necrolysis in a child

被引：16

作者：

Bygum, A

Gregersen, JW

Buus, SK

机构：

[1] Aarhus Kommune Hosp, Dept Dermatol, DK-8000 Aarhus C, Denmark

[2] Skejby Hosp, Dept Immunol, Aarhus, Denmark

来源：

PEDIATRIC DERMATOLOGY | 2004年 / 21卷 / 03期

关键词：

D O I：

10.1111/j.0736-8046.2004.21309.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Toxic epidermal necrolysis (TEN) is a severe, life-threatening disorder that usually affects adults. It is often drug induced. We report an instance of a severe case of TEN in a 6-year-old boy, probably induced by acetaminophen, and less likely by codeine. A lymphocyte stimulation test could not identify the culprit drug. Treatment with intravenous immunoglobulin seemed to halt the disease progression.

引用

收藏

页码：236 / 238

页数：3

相关论文

共 22 条

[1]

Arévalo JM, 2000, J TRAUMA, V48, P473

[2]

BACHOT N, 2001, ALLERGOLOGIE, V24, P214

[3] CLINICAL CLASSIFICATION OF CASES OF TOXIC EPIDERMAL NECROLYSIS, STEVENS-JOHNSON SYNDROME, AND ERYTHEMA MULTIFORME [J].

BASTUJIGARIN, S ;

RZANY, B ;

STERN, RS ;

SHEAR, NH ;

NALDI, L ;

ROUJEAU, JC .

ARCHIVES OF DERMATOLOGY, 1993, 129 (01) :92-96

[4] Plasmapheresis in toxic epidermal necrolysis [J].

Chaidemenos, GC ;

Chrysomallis, F ;

Sombolos, K ;

Mourellou, O ;

Ioannides, D ;

Papakonstantinou, M .

INTERNATIONAL JOURNAL OF DERMATOLOGY, 1997, 36 (03) :218-221

[5] Management of toxic epidermal necrolysis [J].

Craven, NM .

HOSPITAL MEDICINE, 2000, 61 (11) :778-781

[6] Plasmapheresis as an adjunct treatment in toxic epidermal necrolysis [J].

Egan, CA ;

Grant, WJ ;

Morris, SE ;

Saffle, JR ;

Zone, JJ .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1999, 40 (03) :458-461

[7] Antitumour necrosis factor-α antibodies (infliximab) in the treatment of a patient with toxic epidermal necrolysis [J].

Fischer, M ;

Fiedler, E ;

Marsch, WC ;

Wohlrab, J .

BRITISH JOURNAL OF DERMATOLOGY, 2002, 146 (04) :707-708

[8] Toxic epidermal necrolysis and Stevens-Johnson syndrome -: Does early withdrawal of causative drugs decrease the risk of death? [J].

Garcia-Doval, I ;

LeCleach, L ;

Bocquet, H ;

Otero, XL ;

Roujeau, JC .

ARCHIVES OF DERMATOLOGY, 2000, 136 (03) :323-327

[9] IMPROVED BURN CENTER SURVIVAL OF PATIENTS WITH TOXIC EPIDERMAL NECROLYSIS MANAGED WITHOUT CORTICOSTEROIDS [J].

HALEBIAN, PH ;

CORDER, VJ ;

MADDEN, MR ;

FINKLESTEIN, JL ;

SHIRES, GT .

ANNALS OF SURGERY, 1986, 204 (05) :503-512

[10]

Halevi A, 2000, ANN PHARMACOTHER, V34, P32