The rabbit as an animal model for experimental surgery

被引:42
作者
Calasans-Maia, Monica Diuana
Monteiro, Maria Lucia [1 ]
Ascoli, Fabio Oliveira
Granjeiro, Jose Mauro [2 ]
机构
[1] Univ Fed Fluminense, Sch Vet Med, Niteroi, RJ, Brazil
[2] Univ Fed Fluminense, Inst Biol, Niteroi, RJ, Brazil
关键词
Biocompatible Materials; Animal Experimentation; Rabbits; OSSEOUS REPAIR; BONE; HYDROXYAPATITE;
D O I
10.1590/S0102-86502009000400014
中图分类号
R61 [外科手术学];
学科分类号
100210 [外科学];
摘要
The white New Zealand rabbit (Oryctolagus cuniculus) is frequently used as a model for in vivo studies. However, information on precautions when using this animal as an experimental model is limited. This review of the literature covers the gamut from the selection of the animal model all the way to its death, and describes procedures for transporting, raising, breeding, housing, administering anesthesia and handling so as to rationalize the utilization of this species while exploiting its unique characteristics. Based upon the literature and our own experience with white New Zealand rabbits, we conclude that the rabbit is an adequate model for experimental surgery.
引用
收藏
页码:325 / 328
页数:4
相关论文
共 27 条
[1]
AESCHBACHER G, 1995, COMP CONT EDUC PRACT, V17, P1003
[2]
[Anonymous], 1993, GUIDE CARE USE EXPT
[3]
Effect of hydroxyapatite and zinc-containing hydroxyapatite on osseous repair of critical size defect in the rat calvaria [J].
Calasans-Maia, M. ;
Fernandes, G. V. O. ;
Rossi, A. ;
Dias, E. P. ;
Almeida, G. D. S. ;
Mitri, F. F. ;
Granjeiro, J. M. .
BIOCERAMICS, VOL 20, PTS 1 AND 2, 2008, 361-363 :1273-+
[4]
Stimulatory effect on osseous repair of zinc-substituted hydroxyapatite: Histological study in rabbit's tibia [J].
Calasans-Maia, M. ;
Rossi, A. M. ;
Dias, E. P. ;
Santos, S. R. A. ;
Ascoli, F. ;
Granjeiro, J. M. .
BIOCERAMICS, VOL 20, PTS 1 AND 2, 2008, 361-363 :1269-+
[5]
Cantwell Shauna L., 2001, Veterinary Clinics of North America Exotic Animal Practice, V4, P169
[6]
Cardoso E.S., 2007, REV ODONTO CIENC, V22, P66
[7]
Bone mineral measurements of subchondral and trabecular bone in healthy and osteoporotic rabbits [J].
Castañeda, S ;
Largo, R ;
Calvo, E ;
Rodríguez-Salvanés, F ;
Marcos, ME ;
Díaz-Curiel, M ;
Herrero-Beaumont, G .
SKELETAL RADIOLOGY, 2006, 35 (01) :34-41
[8]
Repairing of goat tibial bone defects with BMP-2 gene-modified tissue-engineered bone [J].
Dai, KR ;
Xu, XL ;
Tang, TT ;
Zhu, ZA ;
Yu, CF ;
Lou, JR ;
Zhang, XL .
CALCIFIED TISSUE INTERNATIONAL, 2005, 77 (01) :55-61
[9]
Fagundes D.J., 2004, Acta Cirurgica Brasileira, V19, P59, DOI 10.1590/S0102-86502004000100010
[10]
Ferreira Gabriel Ramalho, 2004, Braz. Dent. J., V15, P175, DOI 10.1590/S0103-64402004000300002