Synthesis of the enantiomer of the antidepressant tranylcypromine

被引：51

作者：

Csuk, R ^{[1
]}

Schabel, MJ ^{[1
]}

vonScholz, Y ^{[1
]}

机构：

[1] UNIV HEIDELBERG,INST PHARMACEUT CHEM,D-69120 HEIDELBERG,GERMANY

来源：

TETRAHEDRON-ASYMMETRY | 1996年 / 7卷 / 12期

关键词：

D O I：

10.1016/S0957-4166(96)00457-0

中图分类号：

O61 [无机化学];

学科分类号：

070301 [无机化学]; 081704 [应用化学];

摘要：

Both enantiomers of the antidepressant tranylcypromine, trans 2-phenyl-cyclopropylamine 1, were prepared in enantiomerically pure form by a chemoenzymatic approach starting from racemic (+/-)-(1RS, 2RS)-trans ethyl 2-phenyl-cyclopropane carboxylate (+/-)-3. Copyright (C) 1996 Elsevier Science Ltd.

引用

页码：3505 / 3512

页数：8

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