Synthesis of immunoreagents for detection of deoxypyrrololine, a cross-link of bone collagen

被引：6

作者：

Adamczyk, M ^{[1
]}

Johnson, DD ^{[1
]}

Reddy, RE ^{[1
]}

机构：

[1] Abbott Labs, Dept Chem 9NM, Diagnost Div, Abbott Pk, IL 60064 USA

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 2000年 / 10卷 / 03期

关键词：

D O I：

10.1016/S0960-894X(99)00682-4

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Two immunogens (5,6) and two probes (fluorescent 7 and chemiluminescent 8) were prepared from benzyl ester (-)-10. These immunoreagents (5,6 and 7,8) are useful for detection of collagen cross-link (+)-deoxypyrrololine (Dpl, 4), and for development of assays for osteoporosis. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：269 / 271

页数：3

共 26 条

[21] IDENTIFICATION OF THE LOCI OF THE COLLAGEN-ASSOCIATED EHRLICH CHROMOGEN IN TYPE-I COLLAGEN CONFIRMS ITS ROLE AS A TRIVALENT CROSS-LINK
KUYPERS, R
TYLER, M
KURTH, LB
JENKINS, ID
HORGAN, DJ
[J]. BIOCHEMICAL JOURNAL, 1992, 283 : 129 - 136
[22] CHEMILUMINESCENT 10-METHYL-ACRIDINIUM-9-(NORMAL-SULPHONYLCARBOXAMIDE) SALTS - SYNTHESIS AND KINETICS OF LIGHT-EMISSION
MATTINGLY, PG
[J]. JOURNAL OF BIOLUMINESCENCE AND CHEMILUMINESCENCE, 1991, 6 (02): : 107 - 114
[23] Rosano TG, 1998, CLIN CHEM, V44, P2126
[24] A COLLAGEN-ASSOCIATED EHRLICH CHROMOGEN - A PYRROLIC CROSS-LINK
SCOTT, JE
HUGHES, EW
SHUTTLEWORTH, A
[J]. BIOSCIENCE REPORTS, 1981, 1 (08) : 611 - 618
[25] Sokoll LJ, 1999, ANAL CHEM, V71, p356R
[26] Wild D., 1994, The Immunoassay Handbook

← 1 2 3 →