Azepines from the intramolecular Prins cyclization of an aminoderivative of lapachol

被引：17

作者：

Camara, CA

Pinto, AC

Vargas, MD

Zukerman-Schpector, J

机构：

[1] Univ Estadual Campinas, Inst Quim, BR-13083970 Campinas, SP, Brazil

[2] Univ Fed Rio de Janeiro, Ctr Tecnol, Inst Quim, BR-21945970 Rio De Janeiro, Brazil

[3] Univ Fed Sao Carlos, Dept Quim, BR-13565905 Sao Carlos, SP, Brazil

来源：

TETRAHEDRON | 2002年 / 58卷 / 30期

基金：

巴西圣保罗研究基金会;

关键词：

azepine; naphthoquinone; lapachol; Prins reaction; ketal hydrolysis;

D O I：

10.1016/S0040-4020(02)00581-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Intramolecular Prins reaction of the 2-(2,2-dimethoxyethylamino)-3-(3-methyl-2-butenyl)-1,4-dihydro-1,4-naphthalene-6,11-dione, an amino derivative of lapachol, under hydrolytic conditions, yielded novel azepines condensed with the naphthoquinone nucleus of lapachol. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：6135 / 6140

页数：6

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