Biological and Medicinal Properties of Grapes and Their Bioactive Constituents: An Update

被引：96

作者：

Yadav, Mukesh ^{[2
]}

Jain, Shalini ^{[8
]}

Bhardwaj, Aarti ^{[5
]}

Nagpal, Ravinder ^{[7
]}

Puniya, Monica ^{[7
]}

Tomar, Radha ^{[2
]}

Singh, Vinod ^{[4
]}

Parkash, Om ^{[6
]}

Prasad, G. B. K. S. ^{[3
]}

Marotta, Francesco ^{[9
]}

Yadav, Hariom ^{[1
]}

机构：

[1] NIDDK, Biol Sect, Diabet Branch, NIH,Clin Res Ctr,West Labs, Bethesda, MD 20892 USA

[2] Jiwaji Univ, SOS Chem, Gwalior, India

[3] Jiwaji Univ, SOS Biochem, Gwalior, India

[4] Barkatullah Univ, Dept Microbiol, Bhopal 462026, Madhya Pradesh, India

[5] Meerut Inst Engn & Technol, Meerut, Uttar Pradesh, India

[6] Natl JALMA Inst Leprosy & Other Mycobacterial Dis, Agra, Uttar Pradesh, India

[7] Natl Dairy Res Inst, Karnal 132001, Haryana, India

[8] Univ Illinois, Urbana, IL 61801 USA

[9] GAIA Fdn, Nutraceut Nutragen Unit, Milan, Italy

来源：

JOURNAL OF MEDICINAL FOOD | 2009年 / 12卷 / 03期

关键词：

biological functions; grapes; phytochemicals; resveratrol; MAMMARY EPITHELIAL-CELLS; BREAST-CANCER CELLS; OXIDATIVE STRESS; RED WINE; SIGNALING PATHWAY; PROSTATE-CANCER; NATURAL-PRODUCT; VITIS-VINIFERA; SEED EXTRACT; NITRIC-OXIDE;

D O I：

10.1089/jmf.2008.0096

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The grape is one of the most valued conventional fruits, worldwide. Although most of the parts of the grapevine are useful, primarily, the grape is considered as a source of unique natural products not only for the development of valuable medicines against a number of diseases, but also for manufacturing various industrial products. Over the last few decades, apart from the chemistry of grape compounds, considerable progress has been made towards exploring the biological activities of various grape-derived constituents. Today, it is well established that in addition to serving as food, the grape is a major source of several phytochemicals. The main biologically active and well-characterized constituent from the grape is resveratrol, which is known for various medicinal properties in human diseases. This review discusses the roles of various grape-derived phytochemicals in relation to various diseases.

引用

页码：473 / 484

页数：12

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