Prostaglandin F synthase

被引：104

作者：

Watanabe, K ^{[1
]}

机构：

[1] Univ E Asia, Div Appl Life Sci, Grad Sch Integrated Sci & Arts, Shimonoseki, Yamaguchi 7518503, Japan

来源：

PROSTAGLANDINS & OTHER LIPID MEDIATORS | 2002年 / 68-9卷

关键词：

PGF synthase; reductase PGF(2 alpha); 9(alpha); 11 beta-PGF(2); aldo-keta reductase family;

D O I：

10.1016/S0090-6980(02)00044-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Prostaglandin (PG) F-2 is synthesized via three pathways from PGE(2), PGD(2), or PGH(2) by PGE 9-ketoreductase, PGD 11-ketoreductase, or PGH 9-, 11-endoperoxide reductase, respectively. The enzymological and molecular biological properties of these enzymes have been reported in work over the last 30 years. Here, these three pathways of PGF synthesis by these enzymes are reviewed, and the physiological roles of the enzymes are discussed. (C) 2002 Elsevier Science Inc. All rights reserved.

引用

页码：401 / 407

页数：7

共 36 条

[1] Detection and regulation of the messenger for a putative bovine endometrial 9-keto-prostaglandin E2 reductase:: Effect of oxytocin and interferon-tau [J].