Prostaglandin F synthase

被引：104

作者：

Watanabe, K ^{[1
]}

机构：

[1] Univ E Asia, Div Appl Life Sci, Grad Sch Integrated Sci & Arts, Shimonoseki, Yamaguchi 7518503, Japan

来源：

PROSTAGLANDINS & OTHER LIPID MEDIATORS | 2002年 / 68-9卷

关键词：

PGF synthase; reductase PGF(2 alpha); 9(alpha); 11 beta-PGF(2); aldo-keta reductase family;

D O I：

10.1016/S0090-6980(02)00044-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Prostaglandin (PG) F-2 is synthesized via three pathways from PGE(2), PGD(2), or PGH(2) by PGE 9-ketoreductase, PGD 11-ketoreductase, or PGH 9-, 11-endoperoxide reductase, respectively. The enzymological and molecular biological properties of these enzymes have been reported in work over the last 30 years. Here, these three pathways of PGF synthesis by these enzymes are reviewed, and the physiological roles of the enzymes are discussed. (C) 2002 Elsevier Science Inc. All rights reserved.

引用

收藏

页码：401 / 407

页数：7

相关论文

共 36 条

[21] PURIFICATION AND PROPERTIES OF PROSTAGLANDIN 9-KETOREDUCTASE FROM PIG AND HUMAN KIDNEY - IDENTITY WITH HUMAN CARBONYL REDUCTASE [J].

SCHIEBER, A ;

FRANK, RW ;

GHISLA, S .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1992, 206 (02) :491-502

[22]

STIER CT, 1987, J PHARMACOL EXP THER, V243, P487

[23]

STIER CT, 1987, P NATL ACAD SCI USA, V84, P256

[24] cDNA cloning, expression, and mutagenesis study of liver-type prostaglandin F synthase [J].

Suzuki, T ;

Fujii, Y ;

Miyano, M ;

Chen, LY ;

Takahashi, T ;

Watanabe, K .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (01) :241-248

[25] Immunocytochemical localization of lung-type prostaglandin F synthase in the rat spinal cord [J].

Suzuki-Yamamoto, T ;

Toida, K ;

Tsuruo, Y ;

Watanabe, K ;

Ishimura, K .

BRAIN RESEARCH, 2000, 877 (02) :391-395

[26] cDNA cloning, expression and characterization of human prostaglandin F synthase [J].

Suzuki-Yamamoto, T ;

Nishizawa, M ;

Fukui, M ;

Okuda-Ashitaka, E ;

Nakajima, T ;

Ito, S ;

Watanabe, K .

FEBS LETTERS, 1999, 462 (03) :335-340

[27] Identification of prostaglandin F-producing cells in the liver [J].

Suzuki-Yamamoto, T ;

Yokoi, H ;

Tsuruo, Y ;

Watanabe, K ;

Ishimura, K .

HISTOCHEMISTRY AND CELL BIOLOGY, 1999, 112 (06) :451-456

[28]

TERRAGNO NA, 1976, ADV PROSTAG THROMB R, V2, P561

[29] Temperature and hemodynamic changes associated with increased neural damage to global hemispheric hypoxic ischemia by prior prostaglandin E2, D2 and F2α administration [J].

Thornhill, J ;

Asselin, J .

PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS, 1999, 61 (04) :207-217

[30] STEREOSPECIFIC CONVERSION OF PROSTAGLANDIN-D2 TO (5Z,13E)-(15S)-9-ALPHA,-11-BETA,15-TRIHYDROXYPROSTA-5,13-DIEN-1-OIC ACID (9-ALPHA,11-BETA-PROSTAGLANDIN-F2) AND OF PROSTAGLANDIN-H2 TO PROSTAGLANDIN-F2-ALPHA BY BOVINE LUNG PROSTAGLANDIN-F SYNTHASE [J].

WATANABE, K ;

IGUCHI, Y ;

IGUCHI, S ;

ARAI, Y ;

HAYAISHI, O ;

ROBERTS, LJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (06) :1583-1587

← 1 2 3 4 →