Histone H1 and chromatin higher-order structure

被引：93

作者：

Ramakrishnan, V ^{[1
]}

机构：

[1] UNIV UTAH,SCH MED,DEPT BIOCHEM,SALT LAKE CITY,UT 84132

来源：

CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION | 1997年 / 7卷 / 03期

关键词：

histone H1; histone H5; chromatin structure; 30 nm filament;

D O I：

10.1615/CritRevEukarGeneExpr.v7.i3.20

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The linker histone H1, or its variants such as H5, have long thought to be involved in promoting the organization of chromatin into a higher-order structure, the 30 nm filament. However, the location of H1 in the filament, its role in filament formation and the structure of the 30 nm filament itself have all been controversial. This article reviews recent results that address these questions.

引用

页码：215 / 230

页数：16

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