Chernobyl-related ionising radiation exposure and cancer risk: an epidemiological review

被引:140
作者
Moysich, KB
Menezes, RJ
Michalek, AM
机构
[1] Roswell Pk Canc Inst, Dept Canc Prevent Epidemiol & Biostat, Buffalo, NY 14226 USA
[2] Roswell Pk Canc Inst, Dept Educ Affairs, Buffalo, NY 14226 USA
关键词
D O I
10.1016/S1470-2045(02)00727-1
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The Chernobyl nuclear accident on 26(th) April, 1986, led to a massive release of radionuclides into the environment. Although vast areas of Europe were affected by Chernobyl-related ionising radiation, the accident had the greatest impact in Belarus, Ukraine, and the Russian Federation. Epidemiological studies that have investigated the link between the Chernobyl accident and cancer have largely focused on malignant diseases in children, specifically thyroid cancer and leukaemia. There is good evidence to suggest that rates of thyroid cancer in children from the countries that were formally part of the Soviet Union have risen as a consequence of the Chernobyl accident. The findings for childhood leukaemia are less conclusive. Overall rates for this disease do not seem to have been affected by the Chernobyl-related ionising radiation, but there may be a larger risk of infant leukaemia in contaminated areas of Europe. Among adult populations, there is no strong evidence to suggest that risk of thyroid cancer, leukaemia, or other malignant disease has increased as a result of the Chernobyl accident.
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页码:269 / 279
页数:11
相关论文
共 72 条
[1]   Epidemiologic and clinical evaluation of thyroid cancer in children from the Gomel region (Belarus) [J].
Antonelli, A ;
Miccoli, P ;
Derzhitski, VE ;
Panasiuk, G ;
Solovieva, N ;
Baschieri, L .
WORLD JOURNAL OF SURGERY, 1996, 20 (07) :867-871
[2]   Chernobyl-related thyroid cancer in children of Belarus: A case-control study [J].
Astakhova, LN ;
Anspaugh, LR ;
Beebe, GW ;
Bouville, A ;
Drozdovitch, VV ;
Garber, V ;
Gavrilin, YI ;
Khrouch, VT ;
Kuvshinnikov, AV ;
Kuzmenkov, YN ;
Minenko, VP ;
Moschik, KV ;
Nalivko, AS ;
Robbins, J ;
Shemiakina, EV ;
Shinkarev, S ;
Tochitskaya, SI ;
Waclawiw, MA .
RADIATION RESEARCH, 1998, 150 (03) :349-356
[3]   FALLOUT FROM CHERNOBYL AND INCIDENCE OF CHILDHOOD LEUKEMIA IN FINLAND, 1976-92 [J].
AUVINEN, A ;
HAKAMA, M ;
ARVELA, H ;
HAKULINEN, T ;
RAHOLA, T ;
SUOMELA, M ;
SODERMAN, B ;
RYTOMAA, T .
BRITISH MEDICAL JOURNAL, 1994, 309 (6948) :151-154
[4]  
BAVERSTOCK K, 1992, NATURE, V359, P21, DOI 10.1038/359021b0
[5]  
Baverstock K F, 1993, World Health Stat Q, V46, P204
[6]  
Boice J. D., 1996, LEUKEMIA, P195
[7]  
BOROVEC J, 1995, ARCH ENVIRON CON TOX, V29, P266
[8]   Cancer risk estimation in Belarussian children due to thyroid irradiation as a consequence of the Chernobyl nuclear accident [J].
Buglova, EE ;
Kenigsberg, JE ;
Sergeeva, NV .
HEALTH PHYSICS, 1996, 71 (01) :45-49
[9]   Thyroid cancer in children and young adults in the North of England. Is increasing incidence related to the Chernobyl accident? [J].
Cotterill, SJ ;
Pearce, MS ;
Parker, L .
EUROPEAN JOURNAL OF CANCER, 2001, 37 (08) :1020-1026
[10]  
Farahati J, 2000, CANCER-AM CANCER SOC, V88, P1470, DOI 10.1002/(SICI)1097-0142(20000315)88:6<1470::AID-CNCR27>3.0.CO