Magnetic resonance microscopy of embryos

被引：49

作者：

Smith, BR

Linney, E

Huff, DS

Johnson, GA

机构：

[1] Box 3302, Department of Radiology, Duke University Medical Center, Durham

[2] Box 3020, Department of Microbiology, Duke University Medical Center, Durham

[3] Department of Pathology, Magee Women's Hospital, Pittsburgh, PA 15213

来源：

COMPUTERIZED MEDICAL IMAGING AND GRAPHICS | 1996年 / 20卷 / 06期

关键词：

magnetic resonance microscopy; embryo; electronic atlas;

D O I：

10.1016/S0895-6111(96)00046-8

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

We demonstrate that magnetic resonance (MR) microscopy provides a mechanism to investigate normal and abnormal developmental anatomy in a non-destructive and distortion-free manner. Techniques for the fixation, embedding, perfusion and image acquisition of embryos between 3 and 30 mm crown rump length are described. We describe the perfusion of a contrast agent to enhance images of the developing embryonic vasculature, Data are acquired as three-dimensional isotropic arrays which permit images to be reformatted retrospectively in any plane. The data are available for archiving, distributing and for post-acquisition manipulations. MR microscopy is a fast technique for producing three-dimensional reconstructions and is free from registration and sectioning artifacts. Copyright (C) 1996 Elsevier Science Ltd.

引用

页码：483 / 490

页数：8

共 14 条

[1]

Bl?mich B., 1992, MAGNETIC RESONANCE M

[2] A HIGH-TEMPERATURE SUPERCONDUCTING RECEIVER FOR NUCLEAR-MAGNETIC-RESONANCE MICROSCOPY [J].