Molecular identification of astroglial neutral amino acid transport systems

被引：8

作者：

Broer, S

机构：

[1] Physiologisch-chemisches, Institut der Universität, Tübingen, Deutschland

来源：

DEVELOPMENTAL NEUROSCIENCE | 1996年 / 18卷 / 5-6期

关键词：

amino acid transport; astrocyte; 4F2; system L;

D O I：

10.1159/000111444

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Astrocytes, like other mammalian cells, possess several different amino acid transport systems with overlapping substrate specificity. They are involved in nutrition of the astrocyte itself and the metabolic traffic between astrocytes and neurons, Recent advances in molecular cloning techniques led to the identification of several amino acid transport proteins, which are in part present in astrocytes as well.

引用

收藏

页码：484 / 491

页数：8

相关论文

共 60 条

[1]

ARRIZA JL, 1993, J BIOL CHEM, V268, P15329

[2] ANION CHANNELS FOR AMINO-ACIDS IN MDCK CELLS [J].

BANDERALI, U ;

ROY, G .

AMERICAN JOURNAL OF PHYSIOLOGY, 1992, 263 (06) :C1200-C1207

[3] EXPRESSION CLONING OF A CDNA FROM RABBIT KIDNEY CORTEX THAT INDUCES A SINGLE TRANSPORT-SYSTEM FOR CYSTINE AND DIBASIC AND NEUTRAL AMINO-ACIDS [J].

BERTRAN, J ;

WERNER, A ;

MOORE, ML ;

STANGE, G ;

MARKOVICH, D ;

BIBER, J ;

TESTAR, X ;

ZORZANO, A ;

PALACIN, M ;

MURER, H .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (12) :5601-5605

[4] STIMULATION OF SYSTEM Y+-LIKE AMINO-ACID-TRANSPORT BY THE HEAVY-CHAIN OF HUMAN 4F2 SURFACE-ANTIGEN IN XENOPUS-LAEVIS OOCYTES [J].

BERTRAN, J ;

MAGAGNIN, S ;

WERNER, A ;

MARKOVICH, D ;

BIBER, J ;

TESTAR, X ;

ZORZANO, A ;

KUHN, LC ;

PALACIN, M ;

MURER, H .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (12) :5606-5610

[5] 2 GLYCINE TRANSPORTER VARIANTS WITH DISTINCT LOCALIZATION IN THE CNS AND PERIPHERAL-TISSUES ARE ENCODED BY A COMMON GENE [J].

BOROWSKY, B ;

MEZEY, E ;

HOFFMAN, BJ .

NEURON, 1993, 10 (05) :851-863

[6] CALMODULIN-DEPENDENT MODULATION OF PH SENSITIVITY OF THE AMINO-ACID-TRANSPORT SYSTEM-L IN HUMAN PLACENTAL CHORIOCARCINOMA CELLS [J].

BRANDSCH, M ;

LEIBACH, FH ;

MAHESH, VB ;

GANAPATHY, V .

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 1994, 1192 (02) :177-184

[7] The 4F2hc surface antigen is necessary for expression of system L-like neutral amino acid-transport activity in C6-BU-1 rat glioma cells: Evidence from expression studies in Xenopus laevis oocytes [J].

Broer, S ;

Broer, A ;

Hamprecht, B .

BIOCHEMICAL JOURNAL, 1995, 312 :863-870

[8] EXPRESSION OF NA+-INDEPENDENT ISOLEUCINE TRANSPORT ACTIVITY FROM RAT-BRAIN IN XENOPUS-LAEVIS OOCYTES [J].

BROER, S ;

BROER, A ;

HAMPRECHT, B .

BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 1994, 1192 (01) :95-100

[9] NEUTRAL AMINO-ACID TRANSPORT IN ASTROCYTES - CHARACTERIZATION OF NA+-DEPENDENT AND NA+-INDEPENDENT COMPONENTS OF ALPHA-AMINOISOBUTYRIC-ACID UPTAKE [J].

BROOKES, N .

JOURNAL OF NEUROCHEMISTRY, 1988, 51 (06) :1913-1918

[10] CYSTINURIA CAUSED BY MUTATIONS IN RBAT, A GENE INVOLVED IN THE TRANSPORT OF CYSTINE [J].

CALONGE, MT ;

GASPARINI, P ;

CHILLARON, J ;

CHILLON, M ;

GALLUCCI, M ;

ROUSAUD, F ;

ZELANTE, L ;

TESTAR, X ;

DALLAPICCOLA, B ;

DISILVERIO, F ;

BARCELO, P ;

ESTIVILL, X ;

ZORZANO, A ;

NUNES, V ;

PALACIN, M .

NATURE GENETICS, 1994, 6 (04) :420-425

← 1 2 3 4 5 6 →