Estrogen, menopause, and the aging brain: How basic neuroscience can inform hormone therapy in women

被引:249
作者
Morrison, John H.
Brinton, Roberta D.
Schmidt, Peter J.
Gore, Andrea C.
机构
[1] Mt Sinai Sch Med, Fishberg Dept Neurosci, Kastor Neurobiol Aging Labs, New York, NY 10029 USA
[2] Mt Sinai Sch Med, Dept Geriatr & Adult Dev, New York, NY 10029 USA
[3] Univ So Calif, Neurosci Program, Dept Biomed Engn, Sch Pharm, Los Angeles, CA 90033 USA
[4] Univ So Calif, Neurosci Program, Dept Mol Pharmacol, Sch Pharm, Los Angeles, CA 90033 USA
[5] Univ So Calif, Neurosci Program, Dept Toxicol, Sch Pharm, Los Angeles, CA 90033 USA
[6] NIMH, Behav Endocrinol Branch, Dept Hlth & Human Serv, NIH, Bethesda, MD 20892 USA
[7] Univ Texas, Div Pharmacol Toxicol, Coll Pharm, Inst Neurosci, Austin, TX 78712 USA
[8] Inst Cell & Mol Biol, Austin, TX 78712 USA
关键词
estradiol; mood; cognition; cerebral cortex; hippocampus; hypothalamus; neuroprotection;
D O I
10.1523/JNEUROSCI.3369-06.2006
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
引用
收藏
页码:10332 / 10348
页数:17
相关论文
共 188 条
[91]  
Matthews KA, 1996, AM J EPIDEMIOL, V143, P971
[92]   Tracking the estrogen receptor in neurons: Implications for estrogen-induced synapse formation [J].
McEwen, B ;
Akama, K ;
Alves, S ;
Brake, WG ;
Bulloch, K ;
Lee, S ;
Li, CJ ;
Yuen, G ;
Milner, TA .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2001, 98 (13) :7093-7100
[93]   Estrogen actions throughout the brain [J].
McEwen, B .
RECENT PROGRESS IN HORMONE RESEARCH, VOL 57: REPRODUCTIVE HORMONES & HUMAN HEALTH, 2002, 57 :357-384
[94]   Estrogen receptor-β potency-selective ligands:: Structure-activity relationship studies of diarylpropionitriles and their acetylene and polar analogues [J].
Meyers, MJ ;
Sun, J ;
Carlson, KE ;
Marriner, GA ;
Katzenellenbogen, BS ;
Katzenellenbogen, JA .
JOURNAL OF MEDICINAL CHEMISTRY, 2001, 44 (24) :4230-4251
[95]   Estrogen replacement therapy, atherosclerosis, and vascular function [J].
Mikkola, TS ;
Clarkson, TB .
CARDIOVASCULAR RESEARCH, 2002, 53 (03) :605-619
[96]   N-methyl-D-aspartate receptor subunit expression in GnRH neurons changes during reproductive senescence in the female rat [J].
Miller, BH ;
Gore, AC .
ENDOCRINOLOGY, 2002, 143 (09) :3568-3574
[97]   Ultrastructural localization of estrogen receptor β immunoreactivity in the rat hippocampal formation [J].
Milner, TA ;
Ayoola, K ;
Drake, CT ;
Herrick, SP ;
Tabori, NE ;
McEwen, BS ;
Warrier, S ;
Alves, SE .
JOURNAL OF COMPARATIVE NEUROLOGY, 2005, 491 (02) :81-95
[98]  
Milner TA, 2001, J COMP NEUROL, V429, P355
[99]   Immunolocalization of estrogen receptor β in the mouse brain:: Comparison with estrogen receptor α [J].
Mitra, SW ;
Hoskin, E ;
Yudkovitz, J ;
Pear, L ;
Wilkinson, HA ;
Hayashi, S ;
Pfaff, DW ;
Ogawa, S ;
Rohrer, SP ;
Schaeffer, JM ;
McEwen, BS ;
Alves, SE .
ENDOCRINOLOGY, 2003, 144 (05) :2055-2067
[100]   Lack of efficacy of estradiol for depression in postmenopausal women: A randomized, controlled trial [J].
Morrison, MF ;
Kallan, MJ ;
Ten Have, T ;
Katz, I ;
Tweedy, K ;
Battistini, M .
BIOLOGICAL PSYCHIATRY, 2004, 55 (04) :406-412