Cell polarity: Posterior par-1 prevents proteolysis

被引：9

作者：

Benton, R ^{[1
]}

St Johnston, D ^{[1
]}

机构：

[1] Univ Cambridge, Dept Genet, Wellcome Trust Canc Res Uk Inst, Cambridge CB2 1QR, England

来源：

CURRENT BIOLOGY | 2002年 / 12卷 / 14期

关键词：

D O I：

10.1016/S0960-9822(02)00962-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The Par-1 kinase is required for anterior-posterior axis formation in Drosophila. New work has identified the posterior determinant, Oskar, as a Par-1 substrate. Phosphorylation stabilises Oskar, revealing a novel mechanism controlling its asymmetric distribution.

引用

页码：R479 / R481

页数：3

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