A novel one-pot four-component access to tetrahydro-β-carbolines by a coupling-amination-aza-annulation-Pictet-Spengler sequence (CAAPS)

被引：61

作者：

Karpov, AS ^{[1
]}

Oeser, T ^{[1
]}

Müller, TJJ ^{[1
]}

机构：

[1] Univ Heidelberg, Inst Organ Chem, D-69120 Heidelberg, Germany

来源：

CHEMICAL COMMUNICATIONS | 2004年 / 13期

关键词：

D O I：

10.1039/b404559a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The four-component coupling-amination-aza-annulation-Pictet-Spengler (CAAPS) sequence of acid chlorides 1, terminal alkynes 2, tryptamine derivatives 6, and acryloyl chloride derivatives 4 represents a facile and rapid one-pot access to tetrahydro-beta-carbolines 7 in moderate to good yields.

引用

页码：1502 / 1503

页数：2

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