Family of the green fluorescent protein: journey to the end of the rainbow

被引:110
作者
Matz, MV
Lukyanov, KA
Lukyanov, SA
机构
[1] Univ Florida, Whitney Lab, St Augustine, FL 32086 USA
[2] RAS, Shemiakin Ovchinnikov Inst Bioorgan Chem, Evrogen JSC, Moscow 117901, Russia
关键词
D O I
10.1002/bies.10154
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Members of the family of the Green Fluorescent Protein (GFP) are the only known type of natural pigments that are essentially encoded by a single gene, since both the substrate for pigment biosynthesis and the necessary catalytic moieties are provided within a single polypeptide chain. In sharp contrast to the state of knowledge just three years ago when GFP was the only known protein of its kind, a whole family of related proteins, exhibiting striking diversity of features have now been identified. This provides new possibilities for a variety of studies ranging from applied biotechnology to evolutionary ecology.
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收藏
页码:953 / 959
页数:7
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