Lipid phase perturbations and the unfolded protein response

被引:26
作者
Ron, D [1 ]
Oyadomari, S
机构
[1] NYU, Sch Med, Skirball Inst Biomol Med, Taipei 10016, Taiwan
[2] NYU, Sch Med, Dept Cell Biol, Taipei 10016, Taiwan
[3] NYU, Sch Med, Dept Med, Taipei 10016, Taiwan
关键词
D O I
10.1016/j.devcel.2004.08.011
中图分类号
Q2 [细胞生物学];
学科分类号
071009 [细胞生物学]; 090102 [作物遗传育种];
摘要
Recent studies of the consequences of ganglioside accumulation in lysosomal storage disease and free cholesterol accumulation in cell membranes in atherosclerosis suggest an unexpected link between perturbation of the endoplasmic reticulum membrane's lipid phase, induction of the unfolded protein response, and cell death.
引用
收藏
页码:287 / 288
页数:2
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