Interferon-γ and colony-stimulating factors as adjuvant therapy for refractory fungal infections in children

被引：76

作者：

Abzug, MJ

Walsh, TJ

机构：

[1] Childrens Hosp, Dept Pediat, Denver, CO 80218 USA

[2] Univ Colorado, Sch Med, Denver, CO 80202 USA

[3] Natl Canc Inst, Immunocompromised Host Sect, Pediat Oncol Branch, Bethesda, MD USA

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2004年 / 23卷 / 08期

关键词：

fungal infection; cytokines; interferon-gamma; colony-stimulating factor; children;

D O I：

10.1097/01.inf.0000134314.65398.bf

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A human immunodeficiency virus-infected boy with Scedosporium apiospermum otomastoiditis and a girl with diabetes mellitus and Mucor sinusitis and orbital cellulitis had life-threatening disease progression despite antifungal treatment. Interferon-gamma and granulocyte-macrophage or granulocyte colony-stimulating factor were added, with good functional outcome in both children. Adjunctive therapy with interferon-gamma, granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor can be considered for refractory invasive fungal infections.

引用

页码：769 / 773

页数：5

共 30 条

[1] ROLE OF GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR AS ADJUVANT THERAPY FOR FUNGAL INFECTION IN PATIENTS WITH CANCER
BODEY, GP
ANAISSIE, E
GUTTERMAN, J
VADHANRAJ, S
[J]. CLINICAL INFECTIOUS DISEASES, 1993, 17 (04) : 705 - 707
[2] Effect of cytokines on the in vitro fungicidal activity of monocytes from paracoccidioidomycosis patients
Calvi, SA
Peraçoli, MTS
Mendes, RP
Marcondes-Machado, J
Fecchio, D
Marques, SA
Soares, AMVC
[J]. MICROBES AND INFECTION, 2003, 5 (02) : 107 - 113
[3] Clemons K V, 2001, Semin Respir Infect, V16, P60
[4] The use of adjuvant interferon-γ therapy for hepatosplenic Blastoschizomyces capitatus infection in a patient with leukemia
DeMaio, J
Colman, L
[J]. CLINICAL INFECTIOUS DISEASES, 2000, 31 (03) : 822 - 824
[5] TREATMENT OF INVASIVE PULMONARY ASPERGILLOSIS IN SEVERELY NEUTROPENIC CHILDREN WITH MALIGNANT DISORDERS USING LIPOSOMAL AMPHOTERICIN-B (AMBISOME), GRANULOCYTE-COLONY-STIMULATING FACTOR, AND SURGERY - REPORT OF 5 CASES
DORNBUSCH, HJ
URBAN, CE
PINTER, H
GINTER, G
FOTTER, R
BECKER, H
MIORINI, T
BERGHOLD, C
[J]. PEDIATRIC HEMATOLOGY AND ONCOLOGY, 1995, 12 (06) : 577 - 586
[6] Frumkin L R, 1997, Curr Opin Hematol, V4, P200
[7] FUKUSHIMA T, 1995, CANCER, V76, P895, DOI 10.1002/1097-0142(19950901)76:5<895::AID-CNCR2820760526>3.0.CO
[8] 2-F
[9] Comparison of interferon-γ, granulocyte colony-stimulating factor, and granulocyte-macrophage colony-stimulating factor for priming leukocyte-mediated hyphal damage of opportunistic fungal pathogens
Gaviria, JM
van Burik, JAH
Dale, DC
Root, RK
Liles, WC
[J]. JOURNAL OF INFECTIOUS DISEASES, 1999, 179 (04) : 1038 - 1041
[10] Modulation of neutrophil-mediated activity against the pseudohyphal form of Candida albicans by granulocyte colony-stimulating factor (G-CSF) administered in vivo
Gaviria, JM
van Burik, JAH
Dale, DC
Root, RK
Liles, WC
[J]. JOURNAL OF INFECTIOUS DISEASES, 1999, 179 (05) : 1301 - 1304

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