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New efficient nickel- and palladium-catalyzed cross-coupling reactions mediated by tetrabutylammonium iodide

被引：98
作者：
Piber, M
Jensen, AE
Rottländer, M
Knochel, P
机构：
[1] Univ Munich, Inst Organ Chem, D-81377 Munich, Germany
[2] H Lundbeck AS, DK-2500 Valby, Denmark
来源：
ORGANIC LETTERS | 1999年 / 1卷 / 09期
关键词：
D O I：
10.1021/ol9907872
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
[GRAPHICS] The addition of Bu(4)Nl has been found to accelerate the palladium(0)-catalyzed cross-coupling between benzylic zinc bromides and aryl or alkenyl triflates. Remarkably, it further allows a new nickel(0)-catalyzed cross-coupling between functionalized benzylic zinc reagents and primary alkyl iodides leading to polyfunctional products in good yields under mild reaction conditions (0-20 degrees C, 4-16 h).
引用
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页码：1323 / 1326
页数：4
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