RIGging an antiviral defense -: it's in the CARDs

被引：49

作者：

Levy, DE ^{[1
]}

Marié, IJ

机构：

[1] NYU, Sch Med, Dept Pathol, New York, NY 10016 USA

[2] NYU, Sch Med, Dept Microbiol, New York, NY 10016 USA

[3] NYU, Sch Med, Dept Pathol, New York, NY 10016 USA

来源：

NATURE IMMUNOLOGY | 2004年 / 5卷 / 07期

关键词：

D O I：

10.1038/ni0704-699

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

How do cells fend off intracellular viruses that slip in below extracellular defensive `radar screens'? The identification of a cytoplasmic RNA helicase that signals through CARD interactions links viral detection to the interferon-beta induction pathway.

引用

页码：699 / 701

页数：3

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