Fate and Transport of Antibiotic Residues and Antibiotic Resistance Genes following Land Application of Manure Waste

被引:711
作者
Chee-Sanford, Joanne C. [1 ,2 ]
Mackie, Roderick I. [3 ,4 ,5 ]
Koike, Satoshi [3 ,4 ]
Krapac, Ivan G. [6 ]
Lin, Yu-Feng [7 ]
Yannarell, Anthony C. [3 ,4 ]
Maxwell, Scott [8 ]
Aminov, Rustam I. [9 ]
机构
[1] USDA ARS, Urbana, IL 61801 USA
[2] Univ Illinois, Dept Crop Sci, Urbana, IL 61801 USA
[3] Univ Illinois, Dept Anim Sci, Urbana, IL 61801 USA
[4] Univ Illinois, Div Nutr Sci, Urbana, IL 61801 USA
[5] Univ Illinois, Inst Genom Biol, Urbana, IL 61801 USA
[6] Illinois State Geol Survey, Champaign, IL 61820 USA
[7] Illinois State Water Survey, Champaign, IL 61820 USA
[8] Univ Illinois, Dept Nat Resources & Environm Sci, Urbana, IL 61801 USA
[9] Rowett Res Inst, Aberdeen AB21 9SB, Scotland
关键词
ESCHERICHIA-COLI O157-H7; MEGASPHAERA-ELSDENII STRAINS; POLYMERASE-CHAIN-REACTION; TIME PCR ASSAYS; TETRACYCLINE RESISTANCE; BACILLUS-SUBTILIS; SWINE-MANURE; PSEUDOMONAS-FLUORESCENS; NATURAL TRANSFORMATION; SALMONELLA-TYPHIMURIUM;
D O I
10.2134/jeq2008.0128
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Antibiotics are used in animal livestock production for therapeutic treatment of disease and at subtherapeutic levels for growth promotion and improvement of feed efficiency. It is estimated that approximately 75% of antibiotics are not absorbed by animals and are excreted in waste. Antibiotic resistance selection occurs among gastrointestinal bacteria, which are also excreted in manure and stored in waste holding systems. Land application of animal waste is a common disposal method used in the United States and is a means For environmental entry of both antibiotics and genetic resistance determinants. Concerns for bacterial resistance gene selection and dissemination of resistance genes have prompted interest about the concentrations and biological activity of drug residues and break-down metabolites, and their fate and transport. Fecal bacteria can survive for weeks to months in the environment, depending on species and temperature, however, genetic elements can persist regardless of cell viability. Phylogenetic analyses indicate antibiotic resistance genes have evolved, although some genes have been maintained in bacteria before the modern antibiotic era. Quantitative measurements of drug residues and levels of resistance genes are needed, in addition to understanding the environmental mechanisms of genetic selection, gene acquisition, and the spatiotemporal dynamics of these resistance genes and their bacterial hosts. This review article discusses an accumulation of findings that address aspects of the fate, transport, and persistence of antibiotics and antibiotic resistance genes in natural environments, with emphasis on mechanisms pertaining to soil environments following land application of animal waste effluent.
引用
收藏
页码:1086 / 1108
页数:23
相关论文
共 292 条
[111]   Extracellular electron transfer [J].
Hernandez, ME ;
Newman, DK .
CELLULAR AND MOLECULAR LIFE SCIENCES, 2001, 58 (11) :1562-1571
[112]  
Heuer H, 2002, FEMS MICROBIOL ECOL, V42, P289, DOI 10.1111/j.1574-6941.2002.tb01019.x
[113]   Manure and sulfadiazine synergistically increased bacterial antibiotic resistance in soil over at least two months [J].
Heuer, Holger ;
Smalla, Kornelia .
ENVIRONMENTAL MICROBIOLOGY, 2007, 9 (03) :657-666
[114]   Fracture aperture measurements and migration of solutes, viruses, and immiscible creosote in a column of clay-rich till [J].
Hinsby, K ;
McKay, LD ;
Jorgensen, P ;
Lenczewski, M ;
Gerba, CP .
GROUND WATER, 1996, 34 (06) :1065-1075
[115]   Occurrence of antibiotics in the aquatic environment [J].
Hirsch, R ;
Ternes, T ;
Haberer, K ;
Kratz, KL .
SCIENCE OF THE TOTAL ENVIRONMENT, 1999, 225 (1-2) :109-118
[116]   Effects of sublethal UVA irradiation on activity levels of oxidative defense enzymes and protein oxidation in Escherichia coli [J].
Hoerter, JD ;
Arnold, AA ;
Kuczynska, DA ;
Shibuya, A ;
Ward, CS ;
Sauer, MG ;
Gizachew, A ;
Hotchkiss, TM ;
Fleming, TJ ;
Johnson, S .
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 2005, 81 (03) :171-180
[117]   KINETICS AND MECHANISM OF DEGRADATION OF AMPICILLIN IN SOLUTION [J].
HOU, JP ;
POOLE, JW .
JOURNAL OF PHARMACEUTICAL SCIENCES, 1969, 58 (04) :447-&
[118]   FECAL BACTERIA IN AGRICULTURAL WATERS OF THE BLUEGRASS REGION OF KENTUCKY [J].
HOWELL, JM ;
COYNE, MS ;
CORNELIUS, P .
JOURNAL OF ENVIRONMENTAL QUALITY, 1995, 24 (03) :411-419
[119]   Statistical dynamics and Walras' law [J].
Huang, WH .
JOURNAL OF ECONOMIC BEHAVIOR & ORGANIZATION, 2001, 46 (01) :57-71
[120]   Effect of length of time before incorporation on survival of pathogenic bacteria present in livestock wastes applied to agricultural soil [J].
Hutchison, ML ;
Walters, LD ;
Moore, A ;
Crookes, KM ;
Avery, SM .
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2004, 70 (09) :5111-5118