Engineering emissive europium and terbium complexes for molecular imaging and sensing

被引：325

作者：

Pandya, Shashi ^{[1
]}

Yu, Junhua ^{[1
]}

Parker, David ^{[1
]}

机构：

[1] Univ Durham, Dept Chem, Durham DH1 3LE, England

来源：

DALTON TRANSACTIONS | 2006年 / 23期

关键词：

D O I：

10.1039/b514637b

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Emissive f-block coordination complexes constitute an important class of optical probes, with applications ranging from sensing of bioactive species, high throughput assays and screening protocols in vitro, to time-resolved imaging studies in cellulo or in vivo. The key chemistry issues to be addressed in complex design and characterisation are defined, with an emphasis on the use of emissive europium and terbium complexes and their conjugates in molecular imaging. Both luminescent 'tags' useful in energy transfer studies and 'responsive' systems for sensing are discussed.

引用

收藏

页码：2757 / 2766

页数：10

相关论文

共 109 条

[1] ENERGY-TRANSFER LUMINESCENCE OF EUROPIUM(III) AND TERBIUM(III) CRYPTATES OF MACROBICYCLIC POLYPYRIDINE LIGANDS [J].

ALPHA, B ;

LEHN, JM ;

MATHIS, G .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1987, 26 (03) :266-267

[2]

[Anonymous], 2005, INVITROGEN MOL PROBE

[3] NMR and luminescence binding studies of ytterbium, thulium, and europium macrocyclic complexes with phosphorus(V) oxy anions [J].

Atkinson, P ;

Bretonnière, Y ;

Parker, D ;

Muller, G .

HELVETICA CHIMICA ACTA, 2005, 88 (03) :391-405

[4] Chemoselective signalling of selected phospho-anions using lanthanide luminescence [J].

Atkinson, P ;

Bretonniere, Y ;

Parker, D .

CHEMICAL COMMUNICATIONS, 2004, (04) :438-439

[5] Luminescent materials and devices: lanthanide azatriphenylene complexes and electroluminescent charge transfer systems [J].

Bakker, BH ;

Goes, M ;

Hoebe, N ;

van Ramesdonk, HJ ;

Verhoeven, JW ;

Werts, MHV ;

Hofstraat, JW .

COORDINATION CHEMISTRY REVIEWS, 2000, 208 :3-16

[6] High-throughput screening for the identification of small-molecule inhibitors of retinoblastoma protein phosphorylation in cells [J].

Barrie, SE ;

Eno-Amooquaye, E ;

Hardcastle, A ;

Platt, G ;

Richards, J ;

Bedford, D ;

Workman, P ;

Aherne, W ;

Mittnacht, S ;

Garrett, MD .

ANALYTICAL BIOCHEMISTRY, 2003, 320 (01) :66-74

[7] Homogeneous time resolved fluorescence resonance energy transfer using rare earth cryptates as a tool for probing molecular interactions in biology [J].

Bazin, H ;

Préaudat, M ;

Trinquet, E ;

Mathis, G .

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2001, 57 (11) :2197-2211

[8] A fluorescent sensor for 2,3-bisphosphoglycerate using a europium tetra-N-oxide bis-bipyridine complex for both binding and signaling purposes [J].

Best, MD ;

Anslyn, EV .

CHEMISTRY-A EUROPEAN JOURNAL, 2003, 9 (01) :51-57

[9] Fine structural specific visualization of RNA on ultrathin sections [J].

Biggiogera, M ;

Fakan, S .

JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 1998, 46 (03) :389-395

[10] Sol gel-immobilised terbium complexes for luminescent sensing of dissolved oxygen by analysis of emission decay [J].

Blair, S ;

Kataky, R ;

Parker, D .

NEW JOURNAL OF CHEMISTRY, 2002, 26 (05) :530-535

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