Consumption of green tea protects rats from exercise-induced oxidative stress in kidney and liver

被引：30

作者：

Alessio, HM ^{[1
]}

Hagerman, AE

Romanello, M

Carando, S

Threlkeld, MS

Rogers, J

Dimitrova, Y

Muhammed, S

Wiley, RL

机构：

[1] Miami Univ, Dept Phys Educ Hlth & Sport Studies, Oxford, OH 45056 USA

[2] Miami Univ, Dept Chem & Biochem, Oxford, OH 45056 USA

[3] Miami Univ, Dept Zool, Oxford, OH 45056 USA

来源：

NUTRITION RESEARCH | 2002年 / 22卷 / 10期

关键词：

tannins; polyphenols; antioxidants; prooxidants; physical activity;

D O I：

10.1016/S0271-5317(02)00421-9

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

The effects of green tea on biomarkers of exercise-induced oxidative status were measured in young male Sprague-Dawley rats. Rats (n = 12) drank green tea or water ad lib for 6.5 weeks. Half of each group was sacrificed at rest, and the other half ran 25 m/min at 0% grade for approximately 30 min immediately before sacrifice. Green tea had no effect on resting heart rate, blood pressure, body weight, cholesterol, or triglycerides. Tea consumption had a mild influence on total plasma antioxidants, heart glutathione, and plasma ascorbic acid. Exercise had a major impact on malonal-dehyde (MDA) equivalents in kidney (+290%, p = 0.0001), and to a lesser extent, liver (+81%, p = 0.18) in rats that drank water. In contrast, kidney MDA equivalents were unchanged by exercise in rats that drank green tea. Green tea may have selective protective effects within the body, especially on the kidney. (C) 2002 Elsevier Science Inc. All rights reserved.

引用

页码：1177 / 1188

页数：12

共 51 条

[11] FREE-RADICALS AND TISSUE-DAMAGE PRODUCED BY EXERCISE [J].

DAVIES, KJA ;

QUINTANILHA, AT ;

BROOKS, GA ;

PACKER, L .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1982, 107 (04) :1198-1205

[12]

Deng ZY, 1998, J AGR FOOD CHEM, V46, P3875, DOI 10.1021/jf980105+

[13] URINARY MALONDIALDEHYDE AS AN INDICATOR OF LIPID-PEROXIDATION IN THE DIET AND IN THE TISSUES [J].

DRAPER, HH ;

POLENSEK, L ;

HADLEY, M ;

MCGIRR, LG .

LIPIDS, 1984, 19 (11) :836-843

[14]

GOLDFARB AH, 1993, MED SCI SPORT EXER, V25, P232

[15] ANALYSIS OF NITRATE, NITRITE, AND [N-15]-LABELED NITRATE IN BIOLOGICAL-FLUIDS [J].

GREEN, LC ;

WAGNER, DA ;

GLOGOWSKI, J ;

SKIPPER, PL ;

WISHNOK, JS ;

TANNENBAUM, SR .

ANALYTICAL BIOCHEMISTRY, 1982, 126 (01) :131-138

[16] High molecular weight plant polyphenolics (tannins) as biological antioxidants [J].

Hagerman, AE ;

Riedl, KM ;

Jones, GA ;

Sovik, KN ;

Ritchard, NT ;

Hartzfeld, PW ;

Riechel, TL .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1998, 46 (05) :1887-1892

[17] DIET AND RISK OF GASTRIC-CANCER - A POPULATION-BASED CASE-CONTROL STUDY IN SWEDEN [J].

HANSSON, LE ;

NYREN, O ;

BERGSTROM, R ;

WOLK, A ;

LINDGREN, A ;

BARON, J ;

ADAMI, HO .

INTERNATIONAL JOURNAL OF CANCER, 1993, 55 (02) :181-189

[18]

HU ML, 1994, METHOD ENZYMOL, V233, P380

[19] Effects of endurance physical training on hydroxyl radical generation in rat tissues [J].

Itoh, H ;

Ohkuwa, T ;

Yamamoto, T ;

Sato, Y ;

Miyamura, M ;

Naoi, M .

LIFE SCIENCES, 1998, 63 (21) :1921-1929

[20] Exercise, oxidative stress, and antioxidants [J].

Ji, LL .

AMERICAN JOURNAL OF SPORTS MEDICINE, 1996, 24 :S20-S24

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