Physiology and pathology of tracheobronchial glands

被引：49

作者：

Finkbeiner, WE ^{[1
]}

机构：

[1] Univ Calif Davis, Med Ctr, Dept Pathol, Sacramento, CA 95817 USA

来源：

RESPIRATION PHYSIOLOGY | 1999年 / 118卷 / 2-3期

关键词：

airways; secretion; tracheobronchial glands; disease; chronic bronchitis; asthma; cystic; fibrosis; hypersecretion;

D O I：

10.1016/S0034-5687(99)00080-8

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

The tracheobronchial glands, composed of mucous and serous secretory cells, provide a mucin-rich, antimicrobial-rich secretion for the conducting airways. The secretory processes of these cells are under complex neurohumoral control. Several diseases demonstrate considerable increases in the volume of secretory glands, the amount of glandular secretions or the character of the secretory product. The role of the tracheobronchial glands in the pathophysiology of chronic bronchitis, asthma and cystic fibrosis is discussed. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

页码：77 / 83

页数：7

共 31 条

[1] Pathophysiology of asthma [J].

Barnes, PJ .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1996, 42 (01) :3-10

[2]

Basbaum C, 1989, LUNG CELL BIOL, P37

[3] Focalized proteolysis: Spatial and temporal regulation of extracellular matrix degradation at the cell surface [J].

Basbaum, CB ;

Werb, Z .

CURRENT OPINION IN CELL BIOLOGY, 1996, 8 (05) :731-738

[4]

BOAT TF, 1994, AIRWAY SECRETION PHY, P217

[5] Developmental mucin gene expression in the human respiratory tract [J].

Buisine, MP ;

Devisme, L ;

Copin, MC ;

Durand-Réville, M ;

Gosselin, B ;

Aubert, JP ;

Porchet, N .

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, 1999, 20 (02) :209-218

[6] Pathological changes according to the severity of asthma [J].

Cho, SH ;

Seo, JY ;

Choi, DC ;

Yoon, HJ ;

Cho, YJ ;

Min, KU ;

Lee, GK ;

Seo, JW ;

Kim, YY .

CLINICAL AND EXPERIMENTAL ALLERGY, 1996, 26 (10) :1210-1219

[7]

ENGLEHARDT JF, 1992, NAT GENET, V2, P240

[8] MARKERS OF MUCUS SECRETION AND DNA LEVELS IN INDUCED SPUTUM FROM ASTHMATIC AND FROM HEALTHY-SUBJECTS [J].

FAHY, JV ;

STEIGER, DJ ;

LIU, J ;

BASBAUM, CB ;

FINKBEINER, WE ;

BOUSHEY, HA .

AMERICAN REVIEW OF RESPIRATORY DISEASE, 1993, 147 (05) :1132-1137

[9] CHLORIDE SECRETION AND FUNCTION OF SEROUS AND MUCOUS CELLS OF HUMAN AIRWAY GLANDS [J].

FINKBEINER, WE ;

SHEN, BQ ;

WIDDICOMBE, JH .

AMERICAN JOURNAL OF PHYSIOLOGY, 1994, 267 (02) :L206-L210

[10]

FINKBEINER WE, 1992, COMPR TREAT, V1, P633

← 1 2 3 4 →