Synthesis of new C-2-symmetsic bioxazoles and application as chiral ligands in asymmetric hydrosilylation

被引：41

作者：

Lee, S ^{[1
]}

Lim, CW ^{[1
]}

Song, CE ^{[1
]}

Kim, IO ^{[1
]}

Jun, CH ^{[1
]}

机构：

[1] YONSEI UNIV, DEPT CHEM, SEOUL 120749, SOUTH KOREA

来源：

TETRAHEDRON-ASYMMETRY | 1997年 / 8卷 / 17期

关键词：

D O I：

10.1016/S0957-4166(97)00353-4

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

New C-2-symmetric chiral (4S,4'S)-bioxazoles 3a and 3b, possessing chirality on their backbone, were synthesized efficiently starting from L-tartaric acid. The structure of 3a was determined by X-ray crystal structure analysis. With these novel chiral bioxazole ligands, as a preliminary investigation for their effects on the enantioselectivity, rhodium(I)-catalyzed enantioselective hydrosilylations of acetophenone were carried out. (C) 1997 Published by Elsevier Science Ltd.

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页码：2927 / 2932

页数：6

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