Of fish and men: using zebrafish to fight human diseases

被引：79

作者：

Ablain, Julien ^{[1
]}

Zon, Leonard I. ^{[1
,2
,3
]}

机构：

[1] Childrens Hosp & Dana Farber Canc Inst, Stem Cell Prgm, Div Hematol Oncol, Boston, MA USA

[2] Howard Hughes Med Inst, Boston, MA USA

[3] Harvard Med Sch, Harvard Stem Cell Inst, Boston, MA USA

来源：

TRENDS IN CELL BIOLOGY | 2013年 / 23卷 / 12期

关键词：

MELANOMA; GENOME; P53;

D O I：

10.1016/j.tcb.2013.09.009

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Long restricted to the field of developmental biology, the use of the zebrafish (Danio rerio) has extended to the study of human pathogenesis. Fostered by the rapid adaptation of new technologies, the design and analysis of fish models of human diseases have contributed important findings that are now making their way from aquariums to clinics. Here we outline the clinical relevance of the zebrafish as a model organism.

引用

页码：584 / 586

页数：3

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