Diffusion-weighted MRI in cyclosporin A neurotoxicity for the classification of cerebral edema

被引：21

作者：

Debaere, C ^{[1
]}

Stadnik, T ^{[1
]}

De Maeseneer, M ^{[1
]}

Osteaux, M ^{[1
]}

机构：

[1] Free Univ Brussels, Acad Hosp, Dept Radiol, B-1090 Brussels, Belgium

来源：

EUROPEAN RADIOLOGY | 1999年 / 9卷 / 09期

关键词：

cyclosporine; diffusion-weighted MRI; brain; vasogenic edema;

D O I：

10.1007/s003300050948

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Cyclosporin A, an immunosuppressive agent, is known to have neurotoxic effects, but until now, there has not been agreement on the underlying mechanism. Our report suggests, by using diffusion-weighted MRI, that the brain lesions caused by cyclosporin A, are probably related to vasogenic edema. This may explain the complete recovery of the lesions on imaging when cyclosporine therapy is stopped.

引用

页码：1916 / 1918

页数：3

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