Zebrafish developmental genetics and central nervous system development

被引：50

作者：

Blader, P ^{[1
]}

Strähle, U ^{[1
]}

机构：

[1] ULP, INSERM, CNRS, IGBMC, F-67404 Illkirch Graffenstaden, France

来源：

HUMAN MOLECULAR GENETICS | 2000年 / 9卷 / 06期

关键词：

D O I：

10.1093/hmg/9.6.945

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The central nervous system (CNS) is the most complex tissue of vertebrates. Recently, the zebrafish has emerged as a powerful genetic system for studying early development, and large-scale mutagenic screens for embryonic patterning defects have been accomplished. Mutants isolated in these screens are proving helpful in unravelling the molecular hierarchies involved in the development of the CNS. We review here recent studies in zebrafish which shed light on the genetic pathways involved in induction and regionalization of the CNS.

引用

页码：945 / 951

页数：7

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