Acanthamoeba castellanii: High antibody prevalence in racially and ethnically diverse populations

被引：41

作者：

Brindley, Neil ^{[2
]}

Matin, Abdul ^{[2
]}

Khan, Naveed Ahmed ^{[1
]}

机构：

[1] Univ Nottingham, Sch Vet Med & Sci, Loughborough LE12 5RD, Leics, England

[2] Univ London, Birkbeck Coll, Sch Biol & Chem Sci, London WC1E 7HU, England

来源：

EXPERIMENTAL PARASITOLOGY | 2009年 / 121卷 / 03期

关键词：

Acanthamoeba; Epidemiology; Prevalence; Protozoa; FREE-LIVING AMEBAS; IGA; SPP;

D O I：

10.1016/j.exppara.2008.11.009

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Acanthamoeba is an opportunistic protozoan pathogen that can produce keratitis and rare but fatal encephalitis. In the present study, we examined secretory IgA antibody to Acanthamoeba castellanii of the T4 genotype in mucosal secretions from 114 individuals of 37 countries, inhabitants and/or visitors, aged 16-65 years in London, UK. Acanthamoeba antibody prevalence rate was more than 85%, without any significant differences between males (86.2%) and females (89.2%). Some epidemiological factors contributing to the high prevalence of antibody to Acanthamoeba in surveyed population are discussed further. (c) 2008 Elsevier Inc. All rights reserved.

引用

页码：254 / 256

页数：3

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