Silica-supported 1,3-dibromo-5,5-dimethylhydantoin (DBH) as a useful reagent for microwave-assisted aromatization of 1,3,5-trisubstituted pyrazolines under solvent-free conditions

被引：55

作者：

Azarifar, D ^{[1
]}

Zolfigol, MA ^{[1
]}

Maleki, B ^{[1
]}

机构：

[1] Bu Ali Sina Univ, Sch Sci, Dept Chem, Hamadan, Iran

来源：

SYNTHESIS-STUTTGART | 2004年 / 11期

关键词：

pyrazolines; 1,3-dibromo-5,5-dimethylhydantoin (DBH); aromatization; solid-surface; microwave irradiation;

D O I：

10.1055/s-2004-829149

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1,3,5-Trisubstituted pyrazolines are rapidly and conveniently oxidized to their corresponding pyrazoles by 1,3-dibromo-5,5-dimethylhydantoin (DBH) under microwave irradiation and solvent-free conditions. The presence of silica gel as a supporting agent is shown to be effective in reducing the reaction times and increasing the yields.

引用

页码：1744 / 1746

页数：3

共 28 条

[1]

[Anonymous], 1993, ORGANIC CHEM USING C

[2] Microwave-assisted synthesis of some 3,5-arylated 2-pyrazolines [J].