Photo-responsive oligonucleotides carrying azobenzene at the 2′-position of uridine

被引：31

作者：

Asanuma, H ^{[1
]}

Yoshida, T ^{[1
]}

Ito, T ^{[1
]}

Komiyama, M ^{[1
]}

机构：

[1] Univ Tokyo, Grad Sch Engn, Dept Chem & Biotechnol, Bunkyo Ku, Tokyo 1138656, Japan

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 45期

关键词：

azo compounds; isomerization; phosphoramidites; photochemistry;

D O I：

10.1016/S0040-4039(99)01547-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Azobenzene residue has been tethered to the 2'-position of uridine in oligonucleotides. On photo-irradiation, the melting temperatures between the modified oligonucleotides and their complementary DNA were significantly changed by the cis-trans isomerization of the azobenzene. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：7995 / 7998

页数：4

共 18 条

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