A coherent transcriptional feed-forward motif model for mediating auxin-sensitive PIN3 expression during lateral root development

被引：67

作者：

Chen, Qian ^{[1
,2
,3
]}

Liu, Yang ^{[1
,2
,4
]}

Maere, Steven ^{[1
,2
]}

Lee, Eunkyoung ^{[5
]}

Van Isterdael, Gert ^{[1
,2
]}

Xie, Zidian ^{[6
,7
]}

Xuan, Wei ^{[1
,2
]}

Lucas, Jessica ^{[5
]}

Vassileva, Valya ^{[1
,2
,8
]}

Kitakura, Saeko ^{[1
,2
,9
]}

Marhavy, Peter ^{[10
,11
]}

Wabnik, Krzysztof ^{[1
,2
,10
]}

Geldner, Niko ^{[11
]}

Benkova, Eva ^{[10
]}

Le, Jie ^{[12
]}

Fukaki, Hidehiro ^{[13
]}

Grotewold, Erich ^{[6
,7
]}

Li, Chuanyou ^{[3
]}

Friml, Jiri ^{[1
,2
,10
]}

Sack, Fred ^{[5
]}

Beeckman, Tom ^{[1
,2
]}

Vanneste, Steffen ^{[1
,2
]}

机构：

[1] Univ Ghent VIB, Dept Plant Syst Biol, B-9052 Ghent, Belgium

[2] Univ Ghent, Dept Plant Biotechnol & Bioinformat, B-9052 Ghent, Belgium

[3] Chinese Acad Sci, Inst Genet & Dev Biol, Natl Ctr Plant Gene Res, State Key Lab Plant Genom, Beijing 100101, Peoples R China

[4] Chinese Acad Agr Sci, Biotechnol Res Inst, Beijing 100081, Peoples R China

[5] Univ British Columbia, Dept Bot, Vancouver, BC V6T 1Z4, Canada

[6] Ohio State Univ, Ctr Appl Plant Sci, Columbus, OH 43210 USA

[7] Ohio State Univ, Dept Mol Genet, Columbus, OH 43210 USA

[8] Bulgarian Acad Sci, Inst Plant Physiol & Genet, BU-1113 Sofia, Bulgaria

[9] Osaka Univ, Grad Sch Sci, Dept Biol Sci, Osaka 5600043, Japan

[10] IST Austria, A-3400 Klosterneuburg, Austria

[11] Univ Lausanne, UNIL Sorge, Dept Plant Mol Biol, CH-1015 Lausanne, Switzerland

[12] Chinese Acad Sci, Inst Bot, Key Lab Plant Mol Physiol, Beijing 100093, Peoples R China

[13] Kobe Univ, Grad Sch Sci, Dept Biol, Kobe, Hyogo 6578501, Japan

来源：

NATURE COMMUNICATIONS | 2015年 / 6卷

基金：

美国国家科学基金会; 加拿大自然科学与工程研究理事会; 欧洲研究理事会;

关键词：

ARABIDOPSIS-THALIANA; RESPONSE ELEMENTS; PLANT DEVELOPMENT; STOMATAL LINEAGE; STRUCTURAL BASIS; LIPS; EFFLUX; NETWORK; TRANSPORT; EMERGENCE;

D O I：

10.1038/ncomms9821

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Multiple plant developmental processes, such as lateral root development, depend on auxin distribution patterns that are in part generated by the PIN-formed family of auxin-efflux transporters. Here we propose that AUXIN RESPONSE FACTOR7 (ARF7) and the ARF7-regulated FOUR LIPS/MYB124 (FLP) transcription factors jointly form a coherent feed-forward motif that mediates the auxin-responsive PIN3 transcription in planta to steer the early steps of lateral root formation. This regulatory mechanism might endow the PIN3 circuitry with a temporal 'memory' of auxin stimuli, potentially maintaining and enhancing the robustness of the auxin flux directionality during lateral root development. The cooperative action between canonical auxin signalling and other transcription factors might constitute a general mechanism by which transcriptional auxin-sensitivity can be regulated at a tissue-specific level.

引用

页数：12

共 61 条

[11] A coherent feedforward loop design principle to sustain robustness of biological networks [J].