Isolation and characterization of the gene encoding the type 5 mouse (Mus musculus) somatostatin receptor (msst(5))

被引:12
作者
Lublin, AL [1 ]
Diehl, NL [1 ]
Hochgeschwender, U [1 ]
机构
[1] NIMH,GENET MOL LAB,NSB,BETHESDA,MD 20892
关键词
gene cloning; nucleotide sequence; expression; RT-PCR;
D O I
10.1016/S0378-1119(97)00156-X
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
We have isolated and determined the nucleotide sequence of the gene for the fifth mouse somatostatin receptor (msst(5)). The gene can encode a protein of 363 amino acid residues (aa). The deduced aa sequence of msst(5) has 97 and 81% identity to the rat and human sst(5) respectively, while it has lower identities with the four other mouse sst(n)s (msst(1)-48%, msst(2)-55%, msst(3)-56%, and msst4-52%). We show that msst(5) is expressed in brain but not in liver, heart, spleen, or kidney of the adult mouse. (C) 1997 Elsevier Science B.V.
引用
收藏
页码:63 / 66
页数:4
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