Palladium(II) chloride/EDTA-catalyzed biaryl homo-coupling of aryl halides in aqueous medium in the presence of ascorbic acid

被引：40

作者：

Ram, Ram N. ^{[1
]}

Singh, Virinder ^{[1
]}

机构：

[1] Indian Inst Technol, Dept Chem, New Delhi 110016, India

来源：

TETRAHEDRON LETTERS | 2006年 / 47卷 / 43期

关键词：

aryl halides; biaryls; reductive homo-coupling; palladium chloride; EDTA; ascorbic acid; aqueous medium;

D O I：

10.1016/j.tetlet.2006.08.056

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Both electron-deficient and electron-rich aryl bromides undergo biaryl homo-coupling in a basic aqueous-ethanotic medium in the presence of PdC12-EDTA (1: 1 molar ratio, 3 mol %) as catalyst and ascorbic acid as reductant (1 mol equiv) in acceptable to good yields. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：7625 / 7628

页数：4

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