Synthesis of rapid responsive gels comprising hydrophilic backbone and poly(N-isopropylacrylamide) graft chains by RAFT polymerization and end-linking processes

被引:33
作者
Liu, Qunfeng
Zhang, Ping
Qing, Aixiang
Lan, Yanxun
Shi, Jianbo
Lu, Mangeng
机构
[1] Chinese Acad Sci, Guangzhou Inst Chem, Guangzhou 510650, Peoples R China
[2] Guangdong Ocean Univ, Coll Sci, Zhanjiang, Guangdong, Peoples R China
[3] Chinese Acad Sci, Grad Sch, Beijing, Peoples R China
[4] Sun Yat Sen Univ, Affiliated Hosp 1, Hosp Otorhinolaryngol, Guangzhou 510630, Peoples R China
关键词
end-linking processes; poly(N-isopropylacrylamide); poly(ethylene glycol);
D O I
10.1016/j.polymer.2006.08.009
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 [高分子化学与物理]; 080501 [材料物理与化学]; 081704 [应用化学];
摘要
A thermosensitive poly(N-isopropylacrylamide) (PNIPAM) grafted gel, which comprises hydrophilic backbone and freely mobile PNIPAM graft chains, was synthesized by reversible addition fragmentation chain transfer (RAFT) polymerization and end-linking processes. Functional PNIPAM bearing dithiobenzoate end group (-C(=S)S-R) was prepared first, and then it was reacted with divinyl compounds to obtain gel. In order to adjust the composition of the gels, two divinyl compounds, N,N-methylenebisacrylamide (BIS) and poly(ethylene glycol) diacrylate (PEGDAC), were used. The cross-linking polymerization mechanism was proposed. The swelling and deswelling kinetics of the hydrogels were measured. The gels exhibit rapid deswelling kinetics. At the same time, they show rapid swelling kinetics within 30 min, whereas a conventional PNIPAM-co-PEG-co-BIS gel with the same feed composition requires more than 10 It to reach swelling equilibrium. (c) 2006 Elsevier Ltd. All rights reserved.
引用
收藏
页码:6963 / 6969
页数:7
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