Total synthesis of (-)-reserpine using the chiron approach

被引：52

作者：

Hanessian, S

Pan, JW

Carnell, A

Bouchard, H

Lesage, L

机构：

[1] Department of Chemistry, Université de Montréal, Station Centreville, Montréal, Que. H3C 3J7

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1997年 / 62卷 / 03期

关键词：

D O I：

10.1021/jo961713w

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A highly stereocontrolled synthesis of ring D/E precursor to reserpine has been developed starting from (-)-quinic acid as a chiral template. The total synthesis of(-)-reserpine is described through the cyclization of an immonium lactam intermediate.

引用

页码：465 / 473

页数：9

共 84 条

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