Quantum Dots - Characterization, Preparation and Usage in Biological Systems

被引：224

作者：

Drbohlavova, Jana ^{[1
]}

Adam, Vojtech ^{[2
]}

Kizek, Rene ^{[2
]}

Hubalek, Jaromir ^{[1
]}

机构：

[1] Brno Univ Technol, Fac Elect Engn & Commun, Dept Microelect, Brno 60200, Czech Republic

[2] Mendel Univ Brno, Fac Agron, Dept Chem & Biochem, Brno 61300, Czech Republic

来源：

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES | 2009年 / 10卷 / 02期

关键词：

Quantum dots; biosensing; biolabeling; template methods; TiO2; CORE/SHELL NANOCRYSTALS; LIVING CELLS; LIVE CELL; NANOPARTICLES; LUMINESCENT; TIO2; FLUORESCENT; SIZE; PHOTOLUMINESCENCE; BIOCONJUGATION;

D O I：

10.3390/ijms10020656

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The use of fluorescent nanoparticles as probes for bioanalytical applications is a highly promising technique because fluorescence-based techniques are very sensitive. Quantum dots (QDs) seem to show the greatest promise as labels for tagging and imaging in biological systems owing to their impressive photostability, which allow long-term observations of biomolecules. The usage of QDs in practical applications has started only recently, therefore, the research on QDs is extremely important in order to provide safe and effective biosensing materials for medicine. This review reports on the recent methods for the preparation of quantum dots, their physical and chemical properties, surface modification as well as on some interesting examples of their experimental use.

引用

收藏

页码：656 / 673

页数：18

相关论文

共 100 条

[1] Functionalized-quantum-dot-liposome hybrids as multimodal nanoparticles for cancer [J].

Al-Jamal, Wafa T. ;

Al-Jamal, Khuloud T. ;

Bomans, Paul H. ;

Frederik, Peter M. ;

Kostarelos, Kostas .

SMALL, 2008, 4 (09) :1406-1415

[2] Wavelength controlled InAs/InP quantum dots for telecom laser applications [J].

Anantathanasarn, S. ;

Notzel, R. ;

van Veldhoven, P. J. ;

van Otten, F. W. M. ;

Barbarin, Y. ;

Servanton, G. ;

de Vries, T. ;

Smalbrugge, E. ;

Geluk, E. J. ;

Eijkemans, T. J. ;

Bente, E. A. J. M. ;

Oei, Y. S. ;

Smit, M. K. ;

Wolter, J. H. .

MICROELECTRONICS JOURNAL, 2006, 37 (12) :1461-1467

[3] New nanostructured TiO2 for direct electrochemistry and glucose sensor applications [J].

Bao, Shu-Juan ;

Li, Chang Ming ;

Zang, Jian-Feng ;

Cui, Xiao-Qiang ;

Qiao, Yan ;

Guo, Jun .

ADVANCED FUNCTIONAL MATERIALS, 2008, 18 (04) :591-599

[4]

BERA D, 2008, J PHYS D, V41, P4

[5] Direct patterning of quantum dots on structured PDMS surface [J].

Bodas, Dhananjay ;

Khan-Malek, Chantal .

SENSORS AND ACTUATORS B-CHEMICAL, 2007, 128 (01) :168-172

[6] Jelly dots: Synthesis and cytotoxicity studies of CdTe quantum dot-gelatin nanocomposites [J].

Byrne, Stephen J. ;

Williams, Yvonne ;

Davies, Anthony ;

Corr, Serena A. ;

Rakovich, Aliaksandra ;

Gun'ko, Yurii K. ;

Rakovich, Yury R. ;

Donegan, John F. ;

Volkov, Yuri .

SMALL, 2007, 3 (07) :1152-1156

[7] Evaluation of quantum dot cytotoxicity based on intracellular uptake [J].

Chang, Emmanuel ;

Thekkek, Nadhi ;

Yu, William W. ;

Colvin, Vicki L. ;

Drezek, Rebekah .

SMALL, 2006, 2 (12) :1412-1417

[8] Fluorescent CdSe/ZnS nanocrystal-peptide conjugates for long-term, nontoxic imaging and nuclear targeting in living cells [J].

Chen, FQ ;

Gerion, D .

NANO LETTERS, 2004, 4 (10) :1827-1832

[9] Non-invasive near infrared fluorescence imaging of CdHgTe quantum dots in mouse model [J].

Chen, Haiyan ;

Wang, Yunqing ;

Xu, Jing ;

Ji, Jinzi ;

Zhang, Jian ;

Hu, Yuzhu ;

Gu, Yueqing .

JOURNAL OF FLUORESCENCE, 2008, 18 (05) :801-811

[10] Preparation and phase transformation of highly ordered TiO2 nanodot arrays on sapphire substrates [J].

Chen, PL ;

Kuo, CT ;

Pan, FM ;

Tsai, TG .

APPLIED PHYSICS LETTERS, 2004, 84 (19) :3888-3890

← 1 2 3 4 5 6 7 8 9 10 →