Reversible binding of fluorescent proteins at DNA-gold nanoparticles

被引：35

作者：

Hazarika, Pompi ^{[1
]}

Kukolka, Florian ^{[1
]}

Niemeyer, Christof M. ^{[1
]}

机构：

[1] Univ Dortmund, Fac Chem, D-44227 Dortmund, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 41期

关键词：

DNA; fluorescence; nanostructures; proteins; supramolecular chemistry;

D O I：

10.1002/anie.200602049

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) Out of bounds: The reversible immobilization of a fluorescent DNA-protein conjugate by strand displacement is achieved by specific DNA hybridization reactions (see picture). Binding and dissociation of the protein can be followed by observation of the protein's fluorescence, which is quenched upon binding to gold nanoparticles. © 2006 Wiley-VCH Verlag GmbH &. Co. KGaA.

引用

收藏

页码：6827 / 6830

页数：4

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