Loss-offunction afleles of the JIL-1 kinase are strong suppressors of position effect variegation of the wm4 allele in Drosophila

被引：24

作者：

Lerach, Stephanie ^{[1
]}

Zhang, Weiguo ^{[1
]}

Bao, Xiaomin ^{[1
]}

Deng, Huai ^{[1
]}

Girton, Jack ^{[1
]}

Johansen, Jorgen ^{[1
]}

Johansen, Kristen M. ^{[1
]}

机构：

[1] Iowa State Univ, Dept Biochem Biophys & Mol Biol, Ames, IA 50011 USA

来源：

GENETICS | 2006年 / 173卷 / 04期

关键词：

D O I：

10.1534/genetics.106.059253

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

In this article we show that hypomorphic loss-of-function alleles of the JIL-1 histone H3S10 kinase are strong suppressors of position effect variegation (PEV) of the w(m4) allele and that lack of JIL-1 activity can counteract the effect of the dominant enhancer E(var)2-1 on PEV.

引用

页码：2403 / 2406

页数：4

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