PROSPECTIVE STUDY OF PERCUTANEOUS ENDOSCOPIC GASTROSTOMY TUBES VERSUS NASOGASTRIC TUBES FOR ENTERAL FEEDING IN PATIENTS WITH HEAD AND NECK CANCER UNDERGOING (CHEMO)RADIATION

被引：138

作者：

Corry, June ^{[1
,2
]}

Poon, Wendy ^{[3
]}

McPhee, Narelle ^{[4
]}

Milner, Alvin D. ^{[5
]}

Cruickshank, Deborah ^{[5
]}

Porceddu, Sandro V. ^{[1
,6
]}

Rischin, Danny ^{[2
,7
]}

Peters, Lester J. ^{[1
,2
]}

机构：

[1] Peter MacCallum Canc Ctr, Div Radiat Oncol, Melbourne, Australia

[2] Univ Melbourne, Peter MacCallum Canc Ctr, Melbourne, Australia

[3] Peter MacCallum Canc Ctr, Div Nursing, Melbourne, Australia

[4] Peter MacCallum Canc Ctr, Dept Nutr, Melbourne, Australia

[5] Peter MacCallum Canc Ctr, Ctr Biostat & Clin Trials, Melbourne, Australia

[6] Princess Alexandra Hosp, Dept Radiat Oncol, Brisbane, Qld 4102, Australia

[7] Peter MacCallum Canc Ctr, Div Haematol & Med Oncol, Melbourne, Australia

来源：

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 2009年 / 31卷 / 07期

关键词：

percutaneous endoscopic gastrostomy tube; nasogastric tube; head and neck cancer; chemoradiation; LOCALLY ADVANCED HEAD; RADIOTHERAPY; RADIATION; PLACEMENT; NUTRITION; CARCINOMA; SUPPORT; IMPACT; TRIAL;

D O I：

10.1002/hed.21044

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 [耳鼻咽喉科学];

摘要：

Background. Percutaneous endoscopic gastrostomy (PEG) tubes have largely replaced nasogastric tubes (NGTs) for nutritional support of patients with head and neck cancer undergoing curative (chemo) radiotherapy without any good scientific basis. Methods. A prospective study was conducted to compare PEG tubes and NGTs in terms of nutritional outcomes, complications, patient satisfaction, and cost. Results. There were 32 PEG and 73 NGT patients. PEG patients sustained significantly less weight loss at 6 weeks post-treatment (median 0.8 kg gain vs 3.7 kg loss, p < .001), but had a high insertion site infection rate (41%), longer median duration of use (146 vs 57 days, p < .001), and more grade 3 dysphagia in disease-free survivors at 6 months (25% vs 8%, p = .07). Patient self-assessed general physical condition and overall quality of life scores were similar in both groups. Overall costs were significantly higher for PEG patients. Conclusion. PEG tube use should be selective, not routine, in this patient population. (C) 2009 Wiley Periodicals, Inc. Head Neck 31: 867-876, 2009

引用

页码：867 / 876

页数：10

共 20 条

[1]

Does feeding tube placement predict for long-term swallowing disability after radiotherapy for head and neck cancer? [J].

Al-Othman, MOF ;

Amdur, RJ ;

Morris, CG ;

Hinerman, RW ;

Mendenhall, WM .

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2003, 25 (09) :741-747

[2]

DEVELOPMENT OF A EUROPEAN-ORGANIZATION-FOR-RESEARCH-AND-TREATMENT-OF-CANCER (EORTC) QUESTIONNAIRE MODULE TO BE USED IN QUALITY-OF-LIFE ASSESSMENTS IN HEAD AND NECK-CANCER PATIENTS [J].

BJORDAL, K ;

AHLNERELMQVIST, M ;

TOLLESSON, E ;

JENSEN, AB ;

RAZAVI, D ;

MAHER, EJ ;

KAASA, S .

ACTA ONCOLOGICA, 1994, 33 (08) :879-885

[3]

Randomized study of percutaneous endoscopic gastrostomy versus nasogastric tubes for enteral feeding in head and neck cancer patients treated with (chemo)radiation [J].

Corry, J. ;

Poon, W. ;

McPhee, N. ;

Milner, A. D. ;

Cruickshank, D. ;

Porceddu, S. V. ;

Rischin, D. ;

Peters, L. J. .

JOURNAL OF MEDICAL IMAGING AND RADIATION ONCOLOGY, 2008, 52 (05) :503-510

[4]

Radiation with concurrent late chemotherapy intensification ('chemoboost') for locally advanced head and neck cancer [J].

Corry, J ;

Rischin, D ;

Smith, JG ;

D'Costa, IA ;

Hughes, PG ;

Sexton, MA ;

Sizeland, A ;

Lyons, B ;

Peters, LJ .

RADIOTHERAPY AND ONCOLOGY, 2000, 54 (02) :123-127

[5]

Percutaneous endoscopic gastrostomy (PEG) -: a long-term follow-up study in head and neck cancer patients [J].

Ehrsson, YT ;

Langius-Eklöf, A ;

Bark, T ;

Laurell, G .

CLINICAL OTOLARYNGOLOGY, 2004, 29 (06) :740-746

[6]

Swallowing outcomes after radiotherapy for head and neck cancer: A systematic review [J].

Frowen, Jacqui J. ;

Perry, Alison R. .

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 2006, 28 (10) :932-944

[7]

GARROW JS, 1993, HUMAN NUTR DIETETICS, P16

[8]

Concomitant boost radiotherapy for squamous carcinoma of the tonsillar fossa [J].

Gwozdz, JT ;

Morrison, WH ;

Garden, AS ;

Weber, RS ;

Peters, LJ ;

Ang, KK .

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1997, 39 (01) :127-135

[9]

Lees J, 1997, Eur J Cancer Care (Engl), V6, P45, DOI 10.1111/j.1365-2354.1997.tb00268.x

[10]

Comparison between nasogastric tube feeding and percutaneous fluoroscopic gastrostomy in advanced head and neck cancer patients [J].

Magné, N ;

Marcy, PY ;

Foa, C ;

Falewee, MN ;

Schneider, M ;

Demard, F ;

Bensadoun, RJ .

EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, 2001, 258 (02) :89-92

← 1 2 →