Highly selective oligonucleotide-based sensor for mercury(II) in aqueous solutions

被引：1144

作者：

Ono, A ^{[1
]}

Togashi, H ^{[1
]}

机构：

[1] Tokyo Metropolitan Univ, Grad Sch Sci, Dept Chem, Hachioji, Tokyo 1920397, Japan

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2004年 / 43卷 / 33期

关键词：

biosensors; fluorescence; FRET (fluorescence resonance energy transfer); mercury; oligonucleotides;

D O I：

10.1002/anie.200454172

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Mercury gauge: An oligodeoxyribonucleotide(ODN)-based sensor, which carries energy-donor and -acceptor moieties (fluorescein, F, and dabcyl, D, respectively), selectively detects HgII ions in aqueous solution. Upon binding HgII ions, the ODN takes on a hairpin structure (see picture); this results in a decrease in the fluorescence emission through enhanced FRET (fluorescence resonance energy transfer) from F to D.

引用

页码：4300 / 4302

页数：3

共 53 条

[41] Aptamer-based folding fluorescent sensor for cocaine
Stojanovic, MN
de Prada, P
Landry, DW
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2001, 123 (21) : 4928 - 4931
[42] A combinatorial approach to discover new chelators for optical metal ion sensing
Szurdoki, F
Ren, DH
Walt, DR
[J]. ANALYTICAL CHEMISTRY, 2000, 72 (21) : 5250 - 5257
[43] TAKEUCHI T., 1962, ACTA NEURO PATHOLOGICA, V2, P40
[44] A novel potassium sensing in aqueous media with a synthetic oligonucleotide derivative. Fluorescence resonance energy transfer associated with guanine quartet-potassium ion complex formation
Ueyama, H
Takagi, M
Takenaka, S
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (48) : 14286 - 14287
[45] Optical fibre reflectance sensors for the detection of heavy metal ions based on immobilised Br-PADAP
Vaughan, AA
Narayanaswamy, R
[J]. SENSORS AND ACTUATORS B-CHEMICAL, 1998, 51 (1-3) : 368 - 376
[46] Volotovskky V, 2003, J MICROBIOL BIOTECHN, V13, P373
[47] Von Burg R., 1991, METALS THEIR COMPOUN, P1045
[48] Photodynamic fluorescent metal ion sensors with parts per billion sensitivity
Winkler, JD
Bowen, CM
Michelet, V
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1998, 120 (13) : 3237 - 3242
[49] Detection of Hg2+ using microcantilever sensors
Xu, XH
Thundat, TG
Brown, GM
Ji, HF
[J]. ANALYTICAL CHEMISTRY, 2002, 74 (15) : 3611 - 3615
[50] Determination of low-level mercury based on a renewable-drops sensing technique
Yang, RH
Wang, KM
Xiao, D
Luo, K
Yang, XH
[J]. FRESENIUS JOURNAL OF ANALYTICAL CHEMISTRY, 2000, 368 (08): : 797 - 802

← 1 2 3 4 5 6 →