Low-dose subcutaneous ketamine infusion and morphine tolerance

被引:66
作者
Bell, RF [1 ]
机构
[1] Haukeland Univ Hosp, Dept Anaesthesiol & Intens Care, Pain Clin, N-5021 Bergen, Norway
关键词
NMDA receptor; tolerance; ketamine; morphine; infusion;
D O I
10.1016/S0304-3959(99)00096-2
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
The NMDA receptor has been reported to be involved in opioid tolerance. Adjuvant subcutaneous infusion treatment with (very) low-dose ketamine, a NMDA receptor antagonist, improves analgesia and at the same time appears to reduce morphine tolerance. Three cases are presented. (C) 1999 International Association for the Study of Pain. Published by Elsevier Science B.V.
引用
收藏
页码:101 / 103
页数:3
相关论文
共 11 条
[11]  
Price DD, 1997, PROG PAIN RES MANAG, V8, P155