A phase III randomized, open-label, controlled trial of chemotherapy and bevacizumab with or without panitumumab in the first-line treatment of patients with metastatic colorectal cancer

被引:24
作者
Wainberg, Zev [1 ]
Hecht, J. Randolph [1 ]
机构
[1] Univ Calif Los Angeles, David Geffen Sch Med, GI Oncol Program, Los Angeles, CA 90095 USA
关键词
epidermal growth factor receptor; 5-fluorouracil; irinotecan; leucovorin; oxaliplatin; vascular endothelial growth factor;
D O I
10.3816/CCC.2006.n.008
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
[No abstract available]
引用
收藏
页码:363 / 367
页数:5
相关论文
共 26 条
[21]  
TABERNERO JM, 2004, P AN M AM SOC CLIN, V23, P248
[22]   FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer:: A randomized GERCOR study [J].
Tournigand, C ;
André, T ;
Achille, E ;
Lledo, G ;
Flesh, M ;
Mery-Mignard, D ;
Quinaux, E ;
Couteau, C ;
Buyse, M ;
Ganem, G ;
Landi, B ;
Colin, P ;
Louvet, C ;
de Gramont, A .
JOURNAL OF CLINICAL ONCOLOGY, 2004, 22 (02) :229-237
[23]  
Weiner LM, 2005, J CLIN ONCOL, V23, p206S
[24]   Untangling the ErbB signalling network [J].
Yarden, Y ;
Sliwkowski, MX .
NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2001, 2 (02) :127-137
[25]  
YASUI W, 1988, CANCER RES, V48, P137
[26]   Dual inhibition of epidermal growth factor receptor and vascular endothelial growth factor receptor phosphorylation by AEE788 reduces growth and metastasis of human colon carcinoma in an orthotopic nude mouse model [J].
Yokoi, K ;
Thaker, PH ;
Yazici, S ;
Rebhun, RR ;
Nam, DH ;
He, JQ ;
Kim, SJ ;
Abbruzzese, JL ;
Hamilton, SR ;
Fidler, IJ .
CANCER RESEARCH, 2005, 65 (09) :3716-3725