Oncogene addiction:: Role of signal attenuation

被引:7
作者
Huebner, Anette [1 ]
Jaeschke, Anja
Davis, Roger J.
机构
[1] Univ Massachusetts, Sch Med, Program Mol Med, Worcester, MA 01605 USA
[2] Howard Hughes Med Inst, Worcester, MA 01605 USA
关键词
D O I
10.1016/j.devcel.2006.11.006
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Tumors can become dependent upon signaling by oncogenes. In a recent issue of Cancer Cell, Sharma et al. (2006b) reported that "oncogene addiction" may be mediated by differential rates of signal attenuation of proapoptotic and prosurvival pathways.
引用
收藏
页码:752 / 754
页数:3
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