The diagnosis of IgE-mediated food allergy in childhood

被引：75

作者：

Du Toit, G. ^{[1
,2
,3
]}

Santos, A. ^{[1
,2
,3
]}

Roberts, G. ^{[4
]}

Fox, A. T. ^{[1
,2
,3
]}

Smith, P. ^{[5
]}

Lack, G. ^{[1
,2
,3
]}

机构：

[1] Kings Coll London, MRC, London WC2R 2LS, England

[2] Kings Coll London, Asthma UK Ctr Allerg Mech Asthma, London WC2R 2LS, England

[3] Guys & St Thomas NHS Fdn Trust, Div Asthma Allergy & Lung Biol, London, England

[4] Univ Child Hlth, Southampton Univ Hosp, NHS Trust, Southampton, Hants, England

[5] Robina & Griffiths Univ, Bond Univ, Southport, Qld, Australia

来源：

PEDIATRIC ALLERGY AND IMMUNOLOGY | 2009年 / 20卷 / 04期

关键词：

allergy diagnosis; children; food allergy; food hypersensitivity; likelihood ratios; oral food challenge; skin prick testing; specific IgE; ATOPY PATCH TEST; COW MILK ALLERGY; 1ST; 3; YEARS; PEANUT ALLERGY; SKIN PRICK; NATURAL-HISTORY; POSITION PAPER; DOUBLE-BLIND; SENSITIZED CHILDREN; EUROPEAN ACADEMY;

D O I：

10.1111/j.1399-3038.2009.00887.x

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

IgE-mediated food allergy is a common condition in childhood and a recognized public health concern. An accurate diagnosis of food allergy facilitates the avoidance of the allergen - and cross-reactive allergens - and allows for safe dietary expansion. The diagnosis of food allergy relies on a combination of rigorous history, physical examination, allergy tests [skin prick tests (SPT) and/or serum-specific IgE] and oral food challenges. Diagnostic cut-off values for SPT and specific IgE results have improved the diagnosis of food allergy and thereby reduced the need to perform oral food challenges. This clinical case series seeks to highlight a contemporary approach to the diagnosis of food allergy in children strategies.

引用

页码：309 / 319

页数：11

共 77 条

[1] Understanding diagnostic tests 2: likelihood ratios, pre- and post-test probabilities and their use in clinical practice [J].