Intraspecies Signaling Involving the Diffusible Signal Factor BDSF (cis-2-Dodecenoic Acid) Influences Virulence in Burkholderia cenocepacia

被引：51

作者：

Ryan, Robert P. ^{[1
]}

McCarthy, Yvonne ^{[1
]}

Watt, Steven A. ^{[2
]}

Niehaus, Karsten ^{[2
]}

Dow, J. Maxwell ^{[1
]}

机构：

[1] Natl Univ Ireland Univ Coll Cork, Dept Microbiol, BioSci Inst, BIOMERIT Res Ctr, Cork, Ireland

[2] Univ Bielefeld, Fac Biol, Dept Proteome & Metabolome Res, D-33501 Bielefeld, Germany

来源：

JOURNAL OF BACTERIOLOGY | 2009年 / 191卷 / 15期

关键词：

PSEUDOMONAS-AERUGINOSA MUTANTS; CYSTIC-FIBROSIS; XANTHOMONAS-CAMPESTRIS; CELL COMMUNICATION; STENOTROPHOMONAS-MALTOPHILIA; TWITCHING MOTILITY; INTESTINAL MUCIN; CEPACIA; SYSTEM; BACTERIA;

D O I：

10.1128/JB.00473-09

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Burkholderia cenocepacia produces a diffusible fatty acid signal molecule, cis-2-dodecenoic acid (BDSF), that has been implicated in interspecies and interkingdom communication. Here, we show that BDSF also acts as an intraspecies signal in B. cenocepacia to control factors contributing to virulence of this major opportunistic pathogen.

引用

页码：5013 / 5019

页数：7

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