Vesicoureteric reflux associated with renal dysplasia in the Wolf-Hirschhorn syndrome

被引：10

作者：

Grisaru, S ^{[1
]}

Ramage, IJ ^{[1
]}

Rosenblum, ND ^{[1
]}

机构：

[1] Univ Toronto, Hosp Sick Children, Dept Pediat, Div Nephrol, Toronto, ON M5G 1XH, Canada

来源：

PEDIATRIC NEPHROLOGY | 2000年 / 14卷 / 02期

关键词：

Wolf-Hirschhorn syndrome; chromosomal anomalies; vesicoureteric reflux; renal dysplasia;

D O I：

10.1007/s004670050031

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Wolf-Hirschhorn syndrome (WHS) is caused by a partial deletion of the short arm of chromosome 4 (4p16.3) and is characterized by severe pre- and postnatal growth retardation, developmental delay, and multiple congenital anomalies, including malformations of the urogenital system. We describe the renal and urinary tract phenotype in a series of six children with WHS. Vesicoureteric reflux was present in four of our six patients (5 of 10 ureters), an abnormality not previously reported in WHS.

引用

页码：146 / 148

页数：3