Ensembl 2007

被引:606
作者
Hubbard, T. J. P.
Aken, B. L.
Beal, K.
Ballester, B.
Caccamo, M.
Chen, Y.
Clarke, L.
Coates, G.
Cunningham, F.
Cutts, T.
Down, T.
Dyer, S. C.
Fitzgerald, S.
Fernandez-Banet, J.
Graf, S.
Haider, S.
Hammond, M.
Herrero, J.
Holland, R.
Howe, K.
Howe, K.
Johnson, N.
Kahari, A.
Keefe, D.
Kokocinski, F.
Kulesha, E.
Lawson, D.
Longden, I.
Melsopp, C.
Megy, K.
Meidl, P.
Overduin, B.
Parker, A.
Prlic, A.
Rice, S.
Rios, D.
Schuster, M.
Sealy, I.
Severin, J.
Slater, G.
Smedley, D.
Spudich, G.
Trevanion, S.
Vilella, A.
Vogel, J.
White, S.
Wood, M.
Cox, T.
Curwen, V.
Durbin, R.
机构
[1] Wellcome Trust Sanger Inst, Hinxton CB10 1SA, Cambs, England
[2] EMBL EBI, Hinxton CB10 1SA, Cambs, England
基金
英国生物技术与生命科学研究理事会;
关键词
D O I
10.1093/nar/gkl996
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The Ensembl (http://www.ensembl.org/) project provides a comprehensive and integrated source of annotation of chordate genome sequences. Over the past year the number of genomes available from Ensembl has increased from 15 to 33, with the addition of sites for the mammalian genomes of elephant, rabbit, armadillo, tenrec, platypus, pig, cat, bush baby, common shrew, microbat and european hedgehog; the fish genomes of stickleback and medaka and the second example of the genomes of the sea squirt (Ciona savignyi) and the mosquito (Aedes aegypti). Some of the major features added during the year include the first complete gene sets for genomes with low-sequence coverage, the introduction of new strain variation data and the introduction of new orthology/paralog annotations based on gene trees.
引用
收藏
页码:D610 / D617
页数:8
相关论文
共 31 条
[1]  
[Anonymous], GENOME BIOL S1
[2]   The Vertebrate Genome Annotation (Vega) database [J].
Ashurst, JL ;
Chen, CK ;
Gilbert, JGR ;
Jekosch, K ;
Keenan, S ;
Meidl, P ;
Searle, SM ;
Stalker, J ;
Storey, R ;
Trevanion, S ;
Wilming, L ;
Hubbard, T .
NUCLEIC ACIDS RESEARCH, 2005, 33 :D459-D465
[3]   Ensembl 2006 [J].
Birney, E. ;
Andrews, D. ;
Caccamo, M. ;
Chen, Y. ;
Clarke, L. ;
Coates, G. ;
Cox, T. ;
Cunningham, F. ;
Curwen, V. ;
Cutts, T. ;
Down, T. ;
Durbin, R. ;
Fernandez-Suarez, X. M. ;
Flicek, P. ;
Graf, S. ;
Hammond, M. ;
Herrero, J. ;
Howe, K. ;
Iyer, V. ;
Jekosch, K. ;
Kahari, A. ;
Kasprzyk, A. ;
Keefe, D. ;
Kokocinski, F. ;
Kulesha, E. ;
London, D. ;
Longden, I. ;
Melsopp, C. ;
Meidl, P. ;
Overduin, B. ;
Parker, A. ;
Proctor, G. ;
Prlic, A. ;
Rae, M. ;
Rios, D. ;
Redmond, S. ;
Schuster, M. ;
Sealy, I. ;
Searle, S. ;
Severin, J. ;
Slater, G. ;
Smedley, D. ;
Smith, J. ;
Stabenau, A. ;
Stalker, J. ;
Trevanion, S. ;
Ureta-Vidal, A. ;
Vogel, J. ;
White, S. ;
Woodwark, C. .
NUCLEIC ACIDS RESEARCH, 2006, 34 :D556-D561
[4]   GeneWise and genomewise [J].
Birney, E ;
Clamp, M ;
Durbin, R .
GENOME RESEARCH, 2004, 14 (05) :988-995
[5]   An overview of ensembl [J].
Birney, E ;
Andrews, TD ;
Bevan, P ;
Caccamo, M ;
Chen, Y ;
Clarke, L ;
Coates, G ;
Cuff, J ;
Curwen, V ;
Cutts, T ;
Down, T ;
Eyras, E ;
Fernandez-Suarez, XM ;
Gane, P ;
Gibbins, B ;
Gilbert, J ;
Hammond, M ;
Hotz, HR ;
Iyer, V ;
Jekosch, K ;
Kahari, A ;
Kasprzyk, A ;
Keefe, D ;
Keenan, S ;
Lehvaslaiho, H ;
McVicker, G ;
Melsopp, C ;
Meidl, P ;
Mongin, E ;
Pettett, R ;
Potter, S ;
Proctor, G ;
Rae, M ;
Searle, S ;
Slater, G ;
Smedley, D ;
Smith, J ;
Spooner, W ;
Stabenau, A ;
Stalker, J ;
Storey, R ;
Ureta-Vidal, A ;
Woodwark, KC ;
Cameron, G ;
Durbin, R ;
Cox, A ;
Hubbard, T ;
Clamp, M .
GENOME RESEARCH, 2004, 14 (05) :925-928
[6]   Data storage and analysis in ArrayExpress [J].
Brazma, Alvis ;
Kapushesky, Misha ;
Parkinson, Helen ;
Sarkans, Ugis ;
Shojatalab, Mohammad .
DNA MICROARRAYS, PART B: DATABASES AND STATISTICS, 2006, 411 :370-+
[7]   The Ensembl computing architecture [J].
Cuff, JA ;
Coates, GMP ;
Cutts, TJR ;
Rae, M .
GENOME RESEARCH, 2004, 14 (05) :971-975
[8]   TranscriptSNPView: a genome-wide catalog of mouse coding variation [J].
Cunningham, Fiona ;
Rios, Daniel ;
Griffiths, Mark ;
Smith, James ;
Ning, Zemin ;
Cox, Tony ;
Flicek, Paul ;
Marin-Garcin, Pablo ;
Herrero, Javier ;
Rogers, Jane ;
Van der Weyden, Louise ;
Bradley, Allan ;
Birney, Ewan ;
Adams, David J. .
NATURE GENETICS, 2006, 38 (08) :853-853
[9]   The Ensembl automatic gene annotation system [J].
Curwen, V ;
Eyras, E ;
Andrews, TD ;
Clarke, L ;
Mongin, E ;
Searle, SMJ ;
Clamp, M .
GENOME RESEARCH, 2004, 14 (05) :942-950
[10]   Tree pattern matching in phylogenetic trees:: automatic search for orthologs or paralogs in homologous gene sequence databases [J].
Dufayard, JF ;
Duret, L ;
Penel, S ;
Gouy, M ;
Rechenmann, F ;
Perrière, G .
BIOINFORMATICS, 2005, 21 (11) :2596-2603