Autoimmune myasthenia gravis In childhood

被引：39

作者：

Andrews, PI

机构：

[1] Sydney Childrens Hosp, Div Neurol, Randwick, NSW 2031, Australia

[2] Univ New S Wales, Kensington, NSW 2033, Australia

来源：

SEMINARS IN NEUROLOGY | 2004年 / 24卷 / 01期

关键词：

juvenile myasthenia gravis; MuSK antibody; seronegative; thymectomy;

D O I：

10.1055/s-2004-829591

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The recent identification of an autoimmune process targeting muscle-specific kinase (MuSK) in a subset of seronegative patients with autoimmune myasthenia gravis promises to improve diagnostic accuracy and redirect therapy in at least some seronegative children and adolescents with myasthenia. Clinical features, diagnostic methods, and management strategies pertinent to children with autoimmune myasthenia are discussed, as well as the emerging data regarding the anti-MuSK autoimmune process in myasthenia gravis.

引用

收藏

页码：101 / 110

页数：10

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