The hammerhead ribozyme

被引：13

作者：

Eckstein, F

机构：

来源：

BIOCHEMICAL SOCIETY TRANSACTIONS | 1996年 / 24卷 / 03期

关键词：

D O I：

10.1042/bst0240601

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：601 / 604

页数：4

共 38 条

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VONKITZING, E ;

LILLEY, DMJ .

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[2] CHEMICAL MODIFICATION OF HAMMERHEAD RIBOZYMES - CATALYTIC ACTIVITY AND NUCLEASE RESISTANCE [J].

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MCSWIGGEN, JA ;

DRAPER, KG ;

GONZALEZ, C ;

JENSEN, K ;

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DIRENZO, AB ;

HAEBERLI, P ;

SWEEDLER, D ;

TRACZ, D ;

GRIMM, S ;

WINCOTT, FE ;

THACKRAY, VG ;

USMAN, N .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (43) :25702-25708

[3] THE HAMMERHEAD RNA DOMAIN, A MODEL RIBOZYME [J].

BRATTY, J ;

CHARTRAND, P ;

FERBEYRE, G ;

CEDERGREN, R .

BIOCHIMICA ET BIOPHYSICA ACTA, 1993, 1216 (03) :345-359

[4] RIBOZYMES AS HUMAN THERAPEUTIC AGENTS [J].

CHRISTOFFERSEN, RE ;

MARR, JJ .

JOURNAL OF MEDICINAL CHEMISTRY, 1995, 38 (12) :2023-2037

[5] EVIDENCE FOR THE ROLE OF SOLVATED METAL HYDROXIDE IN THE HAMMERHEAD CLEAVAGE MECHANISM [J].

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UHLENBECK, OC .

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[6]

ECKSTEIN F, 1996, NUCLEIC ACIDS MOL BI, V10

[7] Nuclease-resistant ribozymes decrease stromelysin mRNA levels in rabbit synovium following exogenous delivery to the knee joint [J].

Flory, CM ;

Pavco, PA ;

Jarvis, TC ;

Lesch, ME ;

Wincott, FE ;

Beigelman, L ;

Hunt, SW ;

Schrier, DJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (02) :754-758

[8] SYNTHETIC OLIGORIBONUCLEOTIDES CARRYING SITE-SPECIFIC MODIFICATIONS FOR RNA STRUCTURE-FUNCTION ANALYSIS [J].

GRASBY, JA ;

GAIT, MJ .

BIOCHIMIE, 1994, 76 (12) :1223-1234

[9]

HASSELOFF J, 1988, NATURE, V334, P585

[10]

HEIDENREICH O, 1992, J BIOL CHEM, V267, P1904

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